Research projects
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At The Florey we research a broad range of topics. We aim to advance brain research on all frontiers – from fundamental research, to drug discovery and clinical work. Explore our scientists’ remarkable work over 200+ projects.

Research projects
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Can we achieve precise medication use in people living with Alzheimer’s disease?
In this project, we will use high-throughput proteomics to profile drug transporter and drug metabolising enzyme expression in Alzheimer's disease (AD) and non-AD human tissues.
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Can we identify novel biomarkers for early detection of Alzheimer’s disease?
This project will screen for antibodies that are uniquely produced in the lymph nodes of pre-symptomatic Alzheimer's disease mice.
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Cell therapy for brain repair focusing on Parkinson’s disease
Proof of principle for cell replacement therapy in the treatment of Parkinson’s disease was first demonstrated in the clinic using human fetal tissue in the 1980s. Key limitations in this technology lie in the availability of donor material, graft survival and ensuring appropriate connectivity of the transplanted cells. Our research is focused on strategies to identify and select the ideal dopamine…
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Cerebral Haemodynamics and Orthostatic Response to Upright Posture in Acute Ischaemic Stroke (CHORUS)
The project aims to evaluate of the extent and clinical relevance of orthostatic changes in cerebral blood flow in acute ischaemic stroke.
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Chemical exposures in utero, child neurodevelopment and epigenetic programming
Exposure to everyday environmental chemicals – e.g. chemicals in plastic products, household chemicals, personal care products – during pregnancy may be harmful to brain development. Globally there is a shared need to better understand how environmental chemicals affect brain development and behaviour. This will inform evidence-based global initiatives that promote healthy brain development in future…
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