Research projects
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At The Florey we research a broad range of topics. We aim to advance brain research on all frontiers – from fundamental research, to drug discovery and clinical work. Explore our scientists’ remarkable work over 200+ projects.
Research projects
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Can we achieve precise medication use in people living with Alzheimer’s disease?
In this project, we will use high-throughput proteomics to profile drug transporter and drug metabolising enzyme expression in Alzheimer's disease (AD) and non-AD human tissues.
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Can we identify novel biomarkers for early detection of Alzheimer’s disease?
In this project, we will screen for antibodies that are uniquely produced in the lymph nodes of pre-symptomatic Alzheimer's disease mice.
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Cell therapy for brain repair focussing on Parkinson’s disease
Proof of principle for cell replacement therapy in the treatment of Parkinson’s disease was first demonstrated in the clinic using human fetal tissue in the 1980’s.
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Cerebral Haemodynamics and Orthostatic Response to Upright Posture in Acute Ischaemic Stroke (CHORUS)
Stroke is the leading cause of adult disability and mortality in Australia. The majority of strokes are ischaemic in nature and occur when a blood vessel to the brain is occluded, usually by a clot.
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Characterisation of a putative new class of brain glial cells with possible roles in Alzheimer’s disease and related disorders
The characteristic neuropathological features of Alzheimer’s disease (AD) are Aβ amyloid plaques and tau neurofibrillary tangles. Our team has discovered a group of glial cells of unknown identity we believe to have key roles in Aβ and tau pathology. The project will investigate the relationship of these cells with Aβ and tau in the human brain and brain from AD-related mouse models.
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