Synaptic biology
Investigating the function and plasticity of the brain, from single molecules to neural networks
Key people
Research Lead
Executive Lead
Research groups
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Epilepsy Functional Genomics Group
The most severe childhood epilepsies are caused by genetic variants in ion channels and synaptic proteins. Their severity is determined by the occurrence of seizures resistant to treatment by anti-seizure medications and accompanied by neurodevelopmental delay, psychiatric manifestations, movement disorders and autism. Our group specializes in modelling these epilepsy forms (also known as developmental and…
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Ion Channels and Human Diseases Group
Our research focuses on understanding the pathology of ion channel disorders, in particular epilepsy, using in vitro and in vivo models to reveal opportunities for developing novel therapies.
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Neural Networks Group
Unlocking the cortex's secrets with advanced techniques and exploring its role in learning, memory, brain cancer and to reveal insights into brain function.
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Neurophysiology of Excitable Networks Group
Our group is focused on understanding the basis of neuronal excitability especially in the context of epilepsy.
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Presynaptic Physiology Group
We research the role of pre-synaptic proteins in neuronal communication in the healthy and diseased state, with a particular focus on neurodevelopmental disorders like intellectual disability, and neurodegenerative disorders like Parkinson's disease.
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