Research projects
At The Florey we research a broad range of topics. We aim to advance brain research on all frontiers – from fundamental research, to drug discovery and clinical work. Explore our scientists’ remarkable work over 200+ projects.
Research projects
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A brain in a dish
One of the major challenges in drug discovery is translating promising therapies from pre-clinical models - usually mice - to clinical use. The lack of suitable human pre-clinical models is a major roadblock for successful translation. To bridge the gap between animal models and human clinical trials, new models of myelin damage and repair using human cells are crucial.
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A network of sites and ‘up-skilled’ therapists to deliver best-practice stroke rehabilitation of the upper limb
Our partnership of clinicians, health providers, consumers, researchers aims to increase access to stroke rehabilitation of the arm and hand.
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A new chemogenetic method that enables functional neural circuit analysis
Neurons within the brain are intricately organized and interconnected to form neural circuits which work collectively and specifically to control behaviour and physiology. Understanding how these neuronal circuits function in the mammalian brain and how they are dysregulated in disease is a major goal in neuroscience research. Two techniques, chemo- and opto-genetics, have revolutionized neuroscience as they…
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A novel treatment for alcohol and nicotine addiction
Through this project we have identified an ion channel that is expressed on select neurons in reward-related brain areas that modulates alcohol intake.
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A stem cell therapy for Hirschsprung Disease
Hirschsprung disease is a common disorder affecting new born children.
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