Research projects
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At The Florey we research a broad range of topics. We aim to advance brain research on all frontiers – from fundamental research, to drug discovery and clinical work. Explore our scientists’ remarkable work over 200+ projects.

Research projects
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Abdominal vagal pathways and their role in anxiety/affective state signalling: targeting vagus nerve stimulation
This project aims to determine whether specific abdominal vagal pathways can be targeted to influence anxiety-related behaviour, potentially providing a more selective alternative to conventional cervical vagus nerve stimulation (VNS). The vagus nerve is central to the gut-brain axis because it provides bidirectional communication between visceral organs and the brain, with approximately 80% of vagal fibres…
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Artefact reduction in functional MRI
Functional MRI (fMRI) is subject to a number of noise sources such as brain pulsation and subject motion that can substantially impact the quality of results.
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Artificial intelligence-based methods for quantitative phenotyping of neural rosettes from microscopy images
This project focuses on building novel image analysis pipelines for analyzing neural rosettes using multi-channel microscopy data. Approaches will include segmentation model development, automated quality control, instance-level morphometrics and spatial modelling of rosette substructures. The goal is to enable high-throughput reproducible quantification of early developmental changes in neurogenetic…
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Assessing the therapeutic impact of chemogenetic stimulation of neuropeptide Y cortical interneurons in MND mouse models
This study will establish whether targeting interneurons in the motor region of the brain is a potential therapeutic target for motor neurone disease.
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Australian Epilepsy Project
The Australian Epilepsy Project aims to improve outcomes for people living with epilepsy by fast-tracking time from diagnosis to seizure control.
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