Translational Cardiovascular and Renal Research Group

Acute kidney injury is defined as a ‘sudden loss of our kidney function’. Even mild episodes of acute kidney injury lead to a greater chance of dying in the hospital, longer stays in hospital, and results in increased healthcare costs (about $400 million in Australia per year). 

Unfortunately, acute kidney injury develops in 30% of patients following open heart surgery (about 3,000 cases in Australia per year). Up to 50% of patients who acquire severe infections (called ‘sepsis’) also develop acute kidney injury (about 7,500 cases in Australia per year). 

There are no effective ways to prevent kidney injury after open heart surgery or sepsis due to our poor understanding of the underlying causes and, inability to assess the risk of kidney injury before it is too late to intervene.

Our research group will use established clinically relevant models of open-heart surgery and sepsis.

  • Location

    Florey Institute of Neuroscience and Mental Health
    30 Royal Parade

  • Research team

    Head Dr Yugeesh Lankadeva

Key collaborators

Professor Clive May, Head of Pre-clinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health

Professor Roger Evans, Monash University

Professor Rinaldo Bellomo, Director of Intensive Care Research Austin Health

Support us

Brain health affects all Australians.
You can support our research by making a donation or a bequest.


Latest breakthroughs, news, events & more.