Rebuilding the brain after stroke
Pluripotent stem cells can be used to generate a wide variety of neuronal subtypes relevant for repair of the central nervous system.
To develop a stem cell based treatment for stroke patients
Recently we showed that cortical neurons can be transplanted into the part of the cortex damaged by a focal stroke and have a remarkable capacity to integrate into the existing host circuitry in order to restore motor function. This project will extend on these findings in order to explore whether we can restore multiple circuits in more severe models of stoke affecting multiple brain region by transplanting multiple neuronal cell types. The project will utilise a number of in vitro and in vivo techniques including: human pluripotent cell culture; immunochemistry; stereotaxic surgery; analysis of animal behaviour; histology and microscopy.
Latest Florey news for Stroke
Mobile Stroke Unit hits the streets of Melbourne
Australia’s first ever dedicated stroke ambulance will hit the road in Melbourne next year to provide the quickest possible diagnosis and reatment for patients suffering a life threatening stroke.
Predicting the impact of a stroke
The Florey is developing a 'stroke atlas' in an exciting initiative to improve global health care
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