
Development of Stem Cell based therapies for Motor Neurone Disease
Recent advances in stem cell biology allow for the on-demand generation of spinal motor neurones from human pluripotent stem cells.
Aims
To develop a stem cell based treatment for motor neurone disease patients
Our laboratory has been exploring the possibility that these neurons can be implanted directly into the spinal cord in order to functionally compensate for those lost to the disease process. This project will seek to understand the capacity for implanted motor neurones to appropriately integrate into host circuitry, including innervation of peripheral targets. We will also explore the concept that the implanted neurones can protect the host neurons from the disease process.
Latest Florey news for Motor neurone disease
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Motor Neurone Disease
The future of MND research - high throughput drug discovery
Associate Professor Bradley Turner is a NHMRC-ARC Dementia Research Leadership Fellow and Head of the Motor Neurone Disease Laboratory, here at The Florey.
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Motor Neurone Disease
Explainer: nature, nurture and neuroplasticity
Neuroplasticity refers to the way in which the cells in the brain (and other parts of the nervous system), change in response to experience. This is not simply a curious by-product of complex evolution but serves important functions such as learning, memor
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