Gut-brain communication – how the stomach and brain communicate

The stomach is the portal to the digestive tract. It tells the brain about its state: how full it is, what is the nature of its contents, are any toxins present.

The brain reacts by eliciting feelings of hunger, satiety, fullness, nausea or wellness. In turn, the brain tells the stomach what to do, after integrating information coming from the stomach and other information, including the sight, smell and proximity of food. For example, the brain can tell the stomach to increase volume to receive food, to mix food, to secrete acid or expel contents.

We are investigating this two-way communication that is essential to a healthy life.


  • Investigate the communication between the brain and the stomach.

Research team


  • Madeleine Di Natale

Take part in this project

Student applications

Students who are applying to study at The Florey can register their interest in this project. Refer to our step-by-step guide to help you with your application.

How to apply

Accepting students

Contact us

If you’re interested in learning more about this project please contact our team.

Please enter your first name
Please enter your last name
Please enter a valid phone number
Please enter a correct email address
Please provide information regarding your enquiry