BioAnalytics Australia

About us

BioAnalytics Australia is a NATA accredited laboratory providing a service to academic and industry partners seeking protein and elemental quantification in biological samples.

Projects are managed in accordance with the Good Clinical Laboratory Practice (GCLP) principles interpreted for research. Non-NATA accredited services are also available.

Quanterix HD-X protein quantification

  • Fully automated HD-X analyser uses single molecule array (Simoa) technology for up to 1000 times greater sensitivity than traditional immunoassays.
  • Protein quantification in plasma, serum and cerebrospinal fluid.
  • Four log dynamic range, detecting proteins at fg/ml concentrations.
  • Highly reproducible, with inter-assay coefficient of variation typically less than 10%.
  • Cost-effective, allowing for multiplexing of up to four proteins in a single assay.
  • NATA accredited and non-NATA accredited Simoa protein quantification services are available.
Quanterix in lab BioAnalytics Australia

Quanterix HD-X assays

Quanterix offer a large range of Simoa assays for a variety of biological processes and diseases. Please visit the Quanterix website for a full list of available assays. Custom Simoa assays can also be developed for additional proteins of interest.

Assays available for key biological processes and diseases include:

Neurology

  • Phosphorylated Tau (pTau 181, 205, 217, and 231)
  • Brain derived Tau (BD-Tau)
  • Amyloid beta 40 and 42
  • Neurofilament light (NFL)
  • Brain derived neurotrophic factor (BDNF)
  • Soluble TREMP2 (sTREM2)
  • TAR DNA binding protein 43 kDa (TDP-43)
  • Postsynaptic density protein 95 kDa (PSD-95)
  • Synaptosomal associated protein 25 kDa (SNAP-25)
  • Ubiquitin carboxyl-terminal hydrolase L1 (UCL-1)
Quanterix machine BioAnalytics Australia

Infectious disease

  • SARS-CoV-2 N protein antigen
  • SARS-CoV-2 spike IGG
  • Human immunodeficiency virus P24 (HIV P24)

Inflammation and immunology

  • Glial fibrillary acidic protein (GFAP)
  • C-Peptide
  • Interferon (IFN- α, γ)
  • Interleukin (IL- 1β, 2, 4, 5, 6, 7, 10, 12, 15, 17A, 22
  • Tumour necrosis factor alpha (TNFα)

Oncology

  • Placental growth factor (PlGF)
  • Programmed cell death protein 1 (PD-1, CD279)
  • Programmed-death ligand 1 (PD-L1, CD274, B7-H1)
  • Prostate specific antigen (PSA)
  • Transforming growth factor beta (TGFβ)

Multiplex assays

Multiplex assays are also available to quantify up to four proteins simultaneously, including:

  • AB40 and AB42
  • NFL and GFAP
  • NFL, GFAP, AB40 and AB42
  • NFL, GFAP, BD-Tau and UCL-L1
  • IL-1β, IL-6, IL-10 and TNFα
  • IL-4, IL-5, IL-13 and IL-17A
  • IL-2, IL-6, IL-8 and IFN-y

ELISA protein quantification

BioAnalytics Australia offers ISO-17025 accredited enzyme linked immunosorbent assay (ELISA) assays for quantifying a range of proteins in biological samples. 

BioAnalytics Australia can also validate other commercially available ELISA kits to extend the range of quantifiable protein biomarkers.

NATA accredited and non-NATA accredited ELISA protein quantification services are available.

BioAnalytics lab

Elemental analysis

With our Agilent 7700x and 8800-QQQ inductively coupled plasma mass spectrometry (ICP-MS) instruments, we can perform highly precise and sensitive trace elemental analysis.

We offer:

  • Routine elemental analysis: using the ICP-MS systems, we offer precise quantification of trace elements (in the ppt to ppb range) across various sample types, with a primary focus on biological samples.
  • 8800 ICP-MS comes equipped with additional triple quad configuration (QQQ), which allows MS/MS analysis. When configured with an additional gas mode (O2), this can enhance interference removal and give rise to higher selectivity for complex samples.
  • Method development and validation: our team provides expertise in developing customised analytical methods tailored to specific research needs.
  • Non-NATA accredited elemental analysis services are also available.

Contact us

Project costs and turnaround times are dependent on the number of proteins to be measured and the number of samples. Please contact BioAnalytics Australia for more information.

  • Adam Southon researcher profile

    Dr Adam Southon, Testing Facility Manager

    E: [email protected]
    P: +61 3 9035 4655
    Melbourne Brain Centre, 245 Burgundy Street, Heidelberg, Victoria 3084