Your source of neuroscience and mental health insights from The Florey.
ReadA Decade of Impact: A Multi-Level Analysis of WiSPP's Impact on Individuals, Institutions, & the Scientific Community. Wheeler, M. A., Tinning, A. & Russell, S. (2024). A Decade Of Impact: A Multi- Level Analysis Of WiSPP’s Impact On Individuals, Institutions, & The Scientific Community. RMIT University, Melbourne. https://doi.org/10.60836/467h-dj22
ReadMultiple Sclerosis (MS) is an immune-mediated disease of the brain and spinal cord, influenced by multiple risk factors, including genetics. Some rare neurological conditions can mimic MS or occur alongside it, making diagnosis challenging. A group of MS researchers, including experts from the Florey, studied 4,340 people with MS and 2,861 without MS to investigate whether rare changes…
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In honour of her late father Graham, Tania West has established The Graham West Research Grant to support Dr Carlos Gantner’s research at The Florey. Graham was just 70 when has passed away from multiple system atrophy, a rare form of atypical Parkinson’s which progresses rapidly and for which there are no effective therapies available. Dr Gantner’s research investigates the sleep…
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FightMND co-founder and former Australian of the Year, Neale Daniher, has attended a major funding announcement hosted at the Florey. The Federal Government is investing $40.1m to create the Neale Daniher National MND Clinical Network to continue the fight against motor neurone disease. The Network will support vital research and give more people, including regional Australians…
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This project focuses on building novel image analysis pipelines for analyzing neural rosettes using multi-channel microscopy data. Approaches will include segmentation model development, automated quality control, instance-level morphometrics and spatial modelling of rosette substructures. The goal is to enable high-throughput reproducible quantification of early developmental changes in neurogenetic…
Learn moreThis project will develop and validate computer vision and signal-processing methods using in-scanner video, real-time head motion tracking and structural MRI to quantify and correct for head motion during MRI. The work will focus on designing approaches to estimate head pose and motion and to evaluate their impact on MRI data quality. This project would be well suited to students with a background in…
Learn moreNeurodegeneration involves progressive neuronal dysfunction, synaptic loss, and ultimately cell death-a process that may unfold slowly in diseases like Alzheimer’s, or rapidly in genetic or metabolic disorders. While the initiating insults vary, many of the downstream mechanisms of neuronal death converge. Our research unites these domains, leveraging insights from inborn errors of metabolism to inform new…
Learn moreFlorey study tackles a ‘missing piece of the puzzle’ in brain cancer research by investigating the influence of cancer cells on the brain. Characterised by their aggressiveness, different cancer grades differentially influence brain cells, with highly aggressive cancer leading to greater neural excitability. Findings further show that this enhanced neural activity directly drives increased…
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Motor neurone disease (MND) is a progressive, fatal neurodegenerative disease. The current first-line treatment for MND was discovered 30 years ago, however more effective treatments are needed. Over the past three decades more than 170 drugs have been tested and failed in MND clinical trials. Researchers at The Florey have developed an innovative stem cell technology to test drugs in the…
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