Rebuilding the brain after stroke

Pluripotent stem cells can be used to generate a wide variety of neuronal subtypes relevant for repair of the central nervous system.

Recently we showed that cortical neurons can be transplanted into the part of the cortex damaged by a focal stroke and have a remarkable capacity to integrate into the existing host circuitry in order to restore motor function.


  • Explore whether we can restore multiple circuits in more severe models of stroke affecting multiple brain region by transplanting multiple neuronal cell types.

The project will utilise a number of in vitro and in vivo techniques including:

  • human pluripotent cell culture
  • immunochemistry
  • stereotaxic surgery
  • analysis of animal behaviour
  • histology and microscopy

Research team

Apply to take part in this project

Student applications

Students who are applying to study at The Florey can register their interest in this project. Refer to our step-by-step guide to help you with your application

Learn how to apply

Accepting students

Contact us

If you’re interested in learning more about this project please contact our team.


Please enter your first name
Please enter your last name
Please enter a valid phone number
Please enter a correct email address
Please provide information regarding your enquiry