Muscarinic receptors and alcohol seeking

We have shown that both muscarinic M4 and M5 receptors are novel targets for regulating alcohol (and other drug) consumption and seeking. Our current focus is examining how and where muscarinic M4 receptors interact with ion channels to modify behaviour.

This program involves in vivo behavioural neuropharmacology in animal models plus in vitro mechanistic studies in cell-based systems.

Aim

  • Examine how and where muscarinic M4 receptors interact with ion channels to modify behaviour.

Research team

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