Multiple system atrophy: a rare Parkinsonism

Multiple system atrophy (MSA) is a rare neurological condition caused by a gradual loss and shrinkage of brain cells. This loss of cells occurs in the parts of the brain that control movement, balance and automatic functions of the body such as bladder and blood pressure.

Treatments and therapies are available to help manage symptoms of MSA, however, there is no cure or ways to prevent it from occurring or slow its progression. Understanding the biology of MSA may give us a better understanding of neurodegenerative diseases. This understanding will help us develop new drugs for MSA and Parkinson’s.


  • To better understand the biology of MSA
  • To develop new treatments for MSA

Other terms sometimes used to describe MSA are ‘olivopontocerebellar atrophy’, ‘striatonigral degeneration, ‘Parkinson’s plus’ and ‘Shy-Drager Syndrome’.

This project involves working with human brain bank material, mouse models of the disease and cell culture.

The Parkinson’s Disease Group adheres to the National Health and Medical council guidelines on the development of a meaningful and authentic engagement with consumers that live with Parkinson’s and Parkinsonism (MSA).

Research team

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Student applications

Students who are applying to study at The Florey can register their interest in this project. Refer to our step-by-step guide to help you with your application.

How to apply

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This project is open for expressions of interest from those wanting to take part in a clinical trial. Contact us to learn more about participating.

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If you’re interested in learning more about this project please contact our team.

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