Neuropeptide Receptor Group

Our group studies G protein-coupled receptors (GPCRs) which represent the most important class of biomolecules for pharmaceutical development, being targeted by ~30 per cent of current drugs.

Our studies on the structure and function of novel neuropeptide GPCRs will enable the development of new drugs to specifically target neurological and other diseases.

About our research

Research interests

  • GPCRs
  • Drug discovery and development

Research team

Research team head

Team members

Research and technical staff

  • Tania Ferraro
  • Sharon Layfield

 

 

PhD students

  • Yasmin Potts
  • Alice Whitehead
  • Andy Zhang
  • Theingi (Tiffany) Myint
  • Renate Roeterink

Master students

  • Jonathan Sher
  • Xintong Zheng

Publications

  • Hossain, M.A. and Bathgate, R.A.D. (2018). Challenges in the design of insulin and relaxin/insulin-like peptide mimetics. Bioorganic & Medicinal Chemistry, [online] 26(10), pp.2827–2841. doi:https://doi.org/10.1016/j.bmc.2017.09.030.
  • ‌Valkovic, A.L., Kocan, M., Hoare, B., Marshall, S., Scott, D.J. and Bathgate, R.A.D. (2022). A Real-Time, Plate-Based BRET Assay for Detection of cGMP in Primary Cells. International Journal of Molecular Sciences, [online] 23(3), p.1908. doi:https://doi.org/10.3390/ijms23031908.
  • Bathgate, R.A.D., Kocan, M., Scott, D.J., Hossain, M.A., Good, S.V., Yegorov, S., Bogerd, J. and Gooley, P.R. (2018). The relaxin receptor as a therapeutic target – perspectives from evolution and drug targeting. Pharmacology & Therapeutics, [online] 187, pp.114–132. doi:https://doi.org/10.1016/j.pharmthera.2018.02.008.

Contact us

Professor Ross Bathgate

Group Head
[email protected]