Neuropeptide Receptor Group

Our group studies G protein-coupled receptors (GPCRs) which represent the most important class of biomolecules for pharmaceutical development, being targeted by ~30 per cent of current drugs.

Our studies on the structure and function of novel neuropeptide GPCRs will enable the development of new drugs to specifically target neurological and other diseases.

About our research

Research interests

  • GPCRs
  • Drug discovery and development

Research team

Research team head

Team members

Research and technical staff

  • Tania Ferraro
  • Sharon Layfield



PhD students

  • Yasmin Potts
  • Alice Whitehead
  • Andy Zhang
  • Theingi (Tiffany) Myint
  • Renate Roeterink



Selected publications

  • Hossain MA and Bathgate RAD (2018), ‘Challenges in the design of insulin and relaxin/insulin-like peptide mimetics’, Bioorganic & Medicinal Chemistry, 26(10):2827–2841, doi:10.1016/j.bmc.2017.09.030
  • ‌Valkovic AL, Kocan M, Hoare B, Marshall S, Scott DJ and Bathgate RAD (2022), ‘A real-time, plate-based BRET assay for detection of cGMP in primary cells’, International Journal of Molecular Sciences, 23(3):1908, doi:10.3390/ijms23031908
  • Bathgate RAD, Kocan M, Scott DJ, Hossain MA, Good SV, Yegorov S, Bogerd J and Gooley PR (2018), ‘The relaxin receptor as a therapeutic target – perspectives from evolution and drug targeting’, Pharmacology & Therapeutics, 187:114–132, doi:10.1016/j.pharmthera.2018.02.008

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