Neuropeptide Receptor Group
Our group studies G protein-coupled receptors (GPCRs), which represent the most important class of biomolecules for pharmaceutical development, being targeted by approximately 30 per cent of current drugs.
Our studies on the structure and function of novel neuropeptide GPCRs will enable the development of new drugs to specifically target neurological and other diseases.
About our research
Research interests
- GPCRs
- Drug discovery and development
Research team
Research team head
Group Head
Team members
Research and technical staff
- Sharon Layfield
PhD students
- Yasmin Potts
- Alice Whitehead
- Andy Zhang
- Renate Roeterink
Selected publications
- Hossain MA and Bathgate RAD (2018), ‘Challenges in the design of insulin and relaxin/insulin-like peptide mimetics’, Bioorganic & Medicinal Chemistry, 26(10):2827–2841, doi:10.1016/j.bmc.2017.09.030
- Valkovic AL, Kocan M, Hoare B, Marshall S, Scott DJ and Bathgate RAD (2022), ‘A real-time, plate-based BRET assay for detection of cGMP in primary cells’, International Journal of Molecular Sciences, 23(3):1908, doi:10.3390/ijms23031908
- Bathgate RAD, Kocan M, Scott DJ, Hossain MA, Good SV, Yegorov S, Bogerd J and Gooley PR (2018), ‘The relaxin receptor as a therapeutic target – perspectives from evolution and drug targeting’, Pharmacology & Therapeutics, 187:114–132, doi:10.1016/j.pharmthera.2018.02.008
Contact us
For more information about our group’s research you can contact us by submitting this form.
