Presynaptic Physiology Group
Our group research the role of pre-synaptic proteins in neuronal communication in the healthy and diseased state, with a particular focus on neurodevelopmental disorders like intellectual disability, and neurodegenerative disorders like Parkinson’s disease.
About our research
Research interests
- Neurodevelopmental disorders
- Neurodegenerative disorders
- Neuronal communication
Research team
Research team head
Group Head
Team members
PhD students
- Elyas Arvell
- Holly Melland
- Paul Park
Master students
- James Carroll
- Joshua Saito
Honours students
- Ali Mulayim
- Nadia Saraya
Publications
- Melland, H., Bumbak, F., Kolesnik-Taylor, A., Ng-Cordell, E., John, A., Constantinou, P., Joss, S., Larsen, M., Fagerberg, C., Laulund, L.W., Thies, J., Emslie, F., Willemsen, M., Kleefstra, T., Pfundt, R., Barrick, R., Chang, R., Loong, L., Alfadhel, M. and Smagt, J. van der (2022). Expanding the genotype and phenotype spectrum of SYT1-associated neurodevelopmental disorder. Genetics in Medicine, [online] 24(4), pp.880–893. doi:https://doi.org/10.1016/j.gim.2021.12.002.
- Luo, J.K., Melland, H., Nithianantharajah, J. and Gordon, S.L. (2021). Postsynaptic Neuroligin-1 Mediates Presynaptic Endocytosis During Neuronal Activity. Frontiers in Molecular Neuroscience, [online] 14, p.744845. doi:https://doi.org/10.3389/fnmol.2021.744845.
- Melland, H., Carr, E.M. and Gordon, S.L. (2020). Disorders of synaptic vesicle fusion machinery. Journal of Neurochemistry, 157(2), pp.130–164. doi:https://doi.org/10.1111/jnc.15181.
Contact us
Dr Sarah Gordon
Group Head
[email protected]