Translational Research and Neuroimaging Stroke Group

The Translational Research and Neuroimaging Stroke Group conducts research into topics including primary and secondary stroke prevention, acute stroke treatment and imaging, atrial fibrillation related to stroke and cryptogenic stroke particularly in younger patients.

Transforming healthcare and rehabilitation for people who have had a stroke is a key focus of our group.

Research interests

  • Primary and secondary stroke prevention
  • Acute stroke treatment and imaging
  • Detecting and linking atrial fibrillation to stroke
  • Mechanisms and genetics of stroke
  • Atrial fibrillation and cryptogenic stroke
Techniques

  • Co-designed interventions and clinical trials
  • Patient-reported outcomes
  • Data and economic evaluation
  • Deep phenotyping
  • Neuroimaging

About our research

Each day in Australia, 18 young people have a stroke. Our aim is to understand why the incidence of stroke is increasing worldwide, particularly in younger patients.

Australia’s first Young Stroke Service is being co-designed with a team of lived-experience consultants and a diverse multidisciplinary investigator team from all over Australia.

This MRFF Rapid Translation Grant currently runs pilot services in Victoria and South Australia.

Research team

Research team head

Team members

Dr Karen Borschmann

Project Manager

Denise Wallis

Global Project Manager

Sarah Amesz

Clinical Services Manager

Emily Ramage

Deep Phenotype Project Lead

Nerida Larkin

Executive Administration

Selected publications

  • Buyck PJ … and Thijs V (2019), ‘Diagnostic accuracy of non-contrast CT imaging markers in cerebral venous thrombosis’, Neurology, 19,92(8):e841-e851, doi:10.1212/WNL.0000000000006959
    Multicenter effort led by Chief Investigator Thijs to identify new diagnostic methods for a rare condition
  • Ma H, Campbell BCV, …l, Vincent Thijs,… Davis SM, Donnan GA (2019), ‘Thrombolysis guided by perfusion imaging up to 9 hours after stroke onset’, New England Journal of Medicine, 9;380(19):1795–1803, doi:10.1056/NEJMoa1813046
    Clinical trial leading to paradigm change in acute stroke research
  • Saposnik G, Bushnell C, Coutinho JM, Field TS, Furie KL, Galadanci N, Kam W, Kirkham FC, McNair ND, Singhal AB, Thijs V, Yang VXD (2024), ‘Diagnosis and management of cerebral venous thrombosis: a scientific statement from the American Heart Association’, Stroke 55(3):e77–e90, doi:10.1161/STR.0000000000000456
    Scientific guideline on rare cause of brain hemorrhage and stroke
  • Bu N, Khlif MS, Lemmens R, Wouters A, Fiebach JB, Chamorro A, Ringelstein EB, Norrving B, Laage R, Grond M, Wilms G, Brodtmann A, Thijs V (2021), ‘Imaging markers of brain frailty and outcome in patients with acute ischemic stroke, Stroke, 52(3):1004–1011, doi:10.1161/STROKEAHA.120.029841
    Study led by Chief Investigator Thijs demonstrating the importance of brain health on stroke outcomes
  • Chen JZ, Thijs VN (2021), ‘Atrial fibrillation following patent foramen ovale closure: systematic review and meta-analysis of observational studies and clinical trials’, Stroke, (5):1653–1661, doi: 10.1161/STROKEAHA.120.030293
    Study led by Chief Investigator Thijs demonstrating the relevance of AF after PFO closure

Contact us

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