Research projects
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At The Florey we research a broad range of topics. We aim to advance brain research on all frontiers – from fundamental research, to drug discovery and clinical work. Explore our scientists’ remarkable work over 200+ projects.
Research projects
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Developing antimicrobial peptide-drug conjugates to treat superbugs
This project aims to develop antimicrobial peptide-based antibiotics that will be effective against superbugs.
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Developing BBB-permeable ASO to target ataxin-2 and mitigate TDP-43 proteinopathies for amyotrophic lateral sclerosis therapy
The cytoplasmic accumulation of TDP-43 in motor neurons is the pathological hallmark of amyotrophic lateral sclerosis (ALS).
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Developing H2 relaxin analog – B7-33 – as antifibrotic therapy
Fibrosis contributes to organ dysfunction and failure. We’ll develop relaxin hormone-based peptides analogues that have strong anti-fibrotic effects.
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Developing H3 relaxin analogs to treat pain
This project will seek to validate RXFP3 as a therapeutic target in the brain for developing new analgesics to manage pain.
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Developing INSL5 analogs as colon motility regulator
This project aims to design and develop novel analogues of INSL5 as potential drug leads for chronic colon motility disorders.
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