Neurochemistry International
Laboratory head - Motor Neurone Disease Laboratory
Associate Professor Bradley Turner
BSc (Hons), PhD (Melb)
A/Prof. Bradley Turner is a NHMRC Dementia Research Leadership Fellow and Head of the Motor Neuron Disease Laboratory. He is a molecular neurobiologist who obtained his PhD in biochemistry at the University of Melbourne in 2005 and trained with Prof. Kay Davies and Prof. Kevin Talbot at the University of Oxford in mouse functional genetics as a NHMRC CJ Martin Fellow for 3 years. He was recruited back to the Florey Institute where he established the MND Laboratory supported by a Stafford Fox Senior Research Fellowship.
He has broad interest in modelling neurodegenerative diseases affecting the motor system using patient stem cell and animal models, spanning pediatric and adult motor neuron diseases. He is a member of the National Health and Medical Research Council Grant Review Panels, Assigners Academy and MND Australia Research Committee.
Key collaborators:
Prof. Kevin Talbot, University of Oxford
Prof. Kay Davies, University of Oxford
Prof. Jean-Philippe Loeffler, University of Strasbourg
Prof. Michael Spedding, Spedding Research Services, Paris
Dr Severine Boillee, Brain and Spine Institute, Paris
Prof. Neil Cashman, University of British Columbia
Prof. Uri Saragovi, McGill University
Prof. Steve Vucic, University of Sydney
A/Prof. Alice Pebay, Centre for Eye Research Australia,
Dr Shyuan Ngo, University of Queensland
Dr Mary-Louise Rogers, Flinders University
A/Prof. Paul Gregorevic, University of Melbourne
Awards and achievements
NHMRC Dementia Research Leadership Fellowship, 2018
Stafford Fox Senior Research Fellowship, 2015
Inaugural Bethlehem Griffiths Research Foundation Young Researcher of the Year Prize, 2010
Research Papers
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Combination of valproic acid and morpholino splice-switching oligonucleotide produces improved outcomes in spinal muscular atrophy patient-derived fibroblasts
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Rilmenidine promotes MTOR-independent autophagy in the mutant SOD1 mouse model of amyotrophic lateral sclerosis without slowing disease progressionAutophagy
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Emerging therapies and challenges in spinal muscular atrophyAnnals of Neurology
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Glutathione monoethyl ester prevents TDP-43 pathology in motor neuronal NSC-34 cellsNeurochemistry International
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Androgen receptor antagonism accelerates disease onset in the SOD1G93Amouse model of amyotrophic lateral sclerosisBritish Journal of Pharmacology
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The P2X7 receptor antagonist JNJ-47965567 administered thrice weekly from disease onset does not alter progression of amyotrophic lateral sclerosis in SOD1G93A micePurinergic Signalling
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Mutant TDP-43 Expression Triggers TDP-43 Pathology and Cell Autonomous Effects on Primary Astrocytes: Implications for Non-cell Autonomous Pathology in ALSNeurochemical Research
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Dysregulation of Steroid Hormone Receptors in Motor Neurons and Glia Associates with Disease Progression in ALS MiceEndocrinology
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Exploring germline recombination in Nestin‐Cre transgenic mice using floxed androgen receptorgenesis
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Amyotrophic Lateral Sclerosis and Autophagy: Dysfunction and Therapeutic TargetingCells
Showing 10 of 63. VIEW ALL
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