T2 relaxometry

T2 relaxometry is a quantitative MR imaging modality that provides an estimate of the T2 relaxation constant of the imaged tissue.

T2 can be altered due to cell damage, with increased T2 relaxation time arising from higher fluid content and potential pathology in the brain in both grey and white matter. Regional T2-relaxometry has been used for many years in the assessment of hippocampal sclerosis at advanced epilepsy imaging centres including here at the Florey. Our team has also developed analysis methods that allow whole-brain T2 maps to be assessed across the entire brain at millimetre spatial resolution.