Sex differences modulating anxiety and binge-drinking behaviours

Excessive alcohol consumption and alcohol use disorders (AUD) are a rising issue in women, yet sex has been largely ignored in pre-clinical research and drug development. This project investigates the neurobiology of binge drinking and anxiety-like behaviours in male and female mice. We use novel neuroscience techniques including RNAscope, confocal microscopy, viral mediated neuronal knockdown and calcium imaging (fiber photometry) to answer these questions.