Bioengineered scaffolds for brain repair
In close collaboration with materials engineers, we are developing and testing various nanofibrous scaffolds and hydrogels to provide structural support for stem cells and differentiating neurons in vitro as well as provide scaffolding support for transplanted neurons in the injured brain.
These scaffolds are designed to closely model the brains extracellular matrix. Furthermore, we are using these scaffolds to provide long-term delivery of functional proteins and viruses – aimed at modulating stem cell proliferation, neuronal differentiation and cell survival.
We adopt an interdisciplinary approach to modelling neural development and repair.
Aims
- Develop and test nanofibrous scaffold and hydrogels to provide structural support for stem cells and differentiating neurons in vitro.
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If you’re interested in learning more about this project please contact our team.