Pre-clinical Critical Care Group

Our laboratory is focused on understanding how genetic, neurochemical and structural changes that occur in the brain following myocardial infarction contributes to an overactive sympathetic nervous system and consequently disease progression into heart failure.

We have recently shown that adult neurogenesis plays a critical role in the regulation of blood pressure. Using a synthetic analogue of the building blocks of DNA our group found that adult neurogenesis in the solitary tract is increased in both genetically and experimentally induced hypertensive models. The main challenge now is to understand how increased neurogenesis within the NTS contributes to hypertension. We believe this research will help us better understand the neurogenic origins of high blood pressure and reveal a new target for treating hypertensive patients.

Research team

Research team head

Professor Clive May

Group Head

Team members

Dr Lindsea Booth

Group Head

Ms Sally Hood

Senior Research Officer

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For more information about our group’s research you can contact us by submitting this form.

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