Professor David Finkelstein

PhD

Physiologist and neurobiologist David Finkelstein is the head of the Parkinson’s Disease Laboratory at the Florey Institute of Neuroscience and Mental Health. In this role, he uses his skills and knowledge to investigate possible new medical interventions for Parkinson’s.

He has led many research projects, authored over 150 research papers in peer-reviewed journals and presented his innovative work to medical researchers all over the world. David is committed to raising awareness of Parkinson’s research within the broader community and increasing the profile of Parkinson’s research in Australia.

He is Chair of Parkinson’s Victoria and advocates for more funding from government grants for Parkinson’s research and support for Parkinson’s services.

Research Papers

Showing 10 of 229. VIEW ALL

Misfolded α-synuclein causes hyperactive respiration without functional deficit in live neuroblastoma cells
Disease Models & Mechanisms
Year: 17/12/2020
Distribution of Parkinson's disease associated RAB39B in mouse brain tissue.
Molecular brain
Year: 30/03/2020
The Long Isoform of Intersectin-1 Has a Role in Learning and Memory.
Frontiers in Behavioral Neuroscience
Year: 25/02/2020
Investigation of nerve pathways mediating colorectal dysfunction in Parkinson’s disease model produced by lesion of nigrostriatal dopaminergic neurons
Neurogastroenterology & Motility
Year: 08/06/2020
Therapeutic applications of chelating drugs in iron metabolic disorders of the brain and retina
Journal of Neuroscience Research
Year: 09/10/2020
Author(s): Ali Shahandeh, Bang V. Bui, David I. Finkelstein, Christine T. O. Nguyen
Author(s): Ali Shahandeh, Bang V. Bui, David I. Finkelstein, Christine T. O. Nguyen
Fibrillar α-synuclein toxicity depends on functional lysosomes
Journal of Biological Chemistry
Year: 18/12/2020
Author(s): Stephanie J. Guiney, Paul A. Adlard, Peng Lei, Celeste H. Mawal, Ashley I. Bush, David I. Finkelstein, Scott Ayton
Author(s): Stephanie J. Guiney, Paul A. Adlard, Peng Lei, Celeste H. Mawal, Ashley I. Bush, David I. Finkelstein, Scott Ayton
Reduced striatal vesicular monoamine transporter 2 in REM sleep behavior disorder: imaging prodromal parkinsonism
Scientific Reports
Year: 12/2020
Parkinsonism as a Third Wave of the COVID-19 Pandemic?
Journal of Parkinson's Disease
Year: 27/10/2020
PrPSc Oligomerization Appears Dynamic, Quickly Engendering Inherent M1000 Acute Synaptotoxicity
Biophysical Journal
Year: 07/2020
An intact membrane is essential for small extracellular vesicle‐induced modulation of α‐synuclein fibrillization
Journal of Extracellular Vesicles
Volume: 10
Year: 12/2020
l ‐3,4‐dihydroxyphenylalanine ( l ‐DOPA) modulates brain iron, dopaminergic neurodegeneration and motor dysfunction in iron overload and mutant alpha‐synuclein mouse models of Parkinson's disease
Journal of Neurochemistry
Year: 28/07/2019
Author(s): Jessica L. Billings, Sarah L. Gordon, Tristan Rawling, Philip A. Doble, Ashley I. Bush, Paul A. Adlard, David I. Finkelstein, Dominic J. Hare
Author(s): Jessica L. Billings, Sarah L. Gordon, Tristan Rawling, Philip A. Doble, Ashley I. Bush, Paul A. Adlard, David I. Finkelstein, Dominic J. Hare
The role of lipids in α-synuclein misfolding and neurotoxicity.
The Journal of biological chemistry
Year: 07/05/2019
The role of lipids in α-synuclein misfolding and neurotoxicity
Journal of Biological Chemistry
Year: 07/06/2019
Author(s): Cathryn L. Ugalde, Victoria A. Lawson, David I. Finkelstein, Andrew F. Hill
Author(s): Cathryn L. Ugalde, Victoria A. Lawson, David I. Finkelstein, Andrew F. Hill
Exercise and physical activity for people with Progressive Supranuclear Palsy: a systematic review.
Clinical rehabilitation
Year: 27/09/2019
Characterising the brain metalloproteome in Down syndrome patients with concomitant Alzheimer's pathology
Metallomics
Year: 2020
Author(s): Nakisa Malakooti, Blaine Roberts, Melanie A. Pritchard, Irene Volitakis, Ron C. Kim, Ira T. Lott, Catriona A. McLean, David I. Finkelstein, Paul A. Adlard
Author(s): Nakisa Malakooti, Blaine Roberts, Melanie A. Pritchard, Irene Volitakis, Ron C. Kim, Ira T. Lott, Catriona A. McLean, David I. Finkelstein, Paul A. Adlard
α-Synuclein Regulates Development and Function of Cholinergic Enteric Neurons in the Mouse Colon.
Neuroscience
Year: 06/11/2019
Migration and Differentiation of Neural Stem Cells Diverted From the Subventricular Zone by an Injectable Self-Assembling β-Peptide Hydrogel.
Frontiers in bioengineering and biotechnology
Year: 08/11/2019
Chronic isolation stress is associated with increased colonic and motor symptoms in the A53T mouse model of Parkinson's disease.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
Year: 10/11/2019
Characterising the brain metalloproteome in Down syndrome patients with concomitant Alzheimer's pathology.
Metallomics : integrated biometal science
Year: 25/11/2019
Regional iron distribution and soluble ferroprotein profiles in the healthy human brain
Progress in Neurobiology
Year: 12/2019
Age modulates the injury-induced metallomic profile in the brain
Metallomics
Year: 2017
Author(s): Portbury, S. D., Hare, D. J., Sgambelloni, C. J., Bishop, D. P., Finkelstein, D. I., Doble, P. A., Adlard, P. A.
Author(s): Portbury, S. D., Hare, D. J., Sgambelloni, C. J., Bishop, D. P., Finkelstein, D. I., Doble, P. A., Adlard, P. A.
Analogues of desferrioxamine B designed to attenuate iron-mediated neurodegeneration: synthesis, characterisation and activity in the MPTP-mouse model of Parkinson's disease
Metallomics
Volume: 9
Page(s): 852-864
Year: 2017
Author(s): Gotsbacher, M. P., Telfer, T. J., Witting, P. K., Double, K. L., Finkelstein, D. I., Codd, R.
Author(s): Gotsbacher, M. P., Telfer, T. J., Witting, P. K., Double, K. L., Finkelstein, D. I., Codd, R.
Acute Neurotoxicity Models of Prion Disease
Acs Chemical Neuroscience
Volume: 9
Page(s): 431-445
Year: 2018
Author(s): Islam, A. M. T., Adlard, P. A., Finkelstein, D. I., Lewis, V., Biggi, S., Biasini, E., Collins, S. J.
Author(s): Islam, A. M. T., Adlard, P. A., Finkelstein, D. I., Lewis, V., Biggi, S., Biasini, E., Collins, S. J.
Modulating Protein Phosphatase 2A Rescues Disease Phenotype in Neurodegenerative Tauopathies.
ACS chemical neuroscience
Year: 2018
Author(s): McKenzie-Nickson, Simon, Chan, Jacky, Perez, Keyla, Hung, Lin W, Cheng, Lesley, Sedjahtera, Amelia, Gunawan, Lydia, Adlard, Paul A, Hayne, David J, McInnes, Lachlan E, Donnelly, Paul S, Finkelstein, David I, Hill, Andrew F, Barnham, Kevin J
Author(s): McKenzie-Nickson, Simon, Chan, Jacky, Perez, Keyla, Hung, Lin W, Cheng, Lesley, Sedjahtera, Amelia, Gunawan, Lydia, Adlard, Paul A, Hayne, David J, McInnes, Lachlan E, Donnelly, Paul S, Finkelstein, David I, Hill, Andrew F, Barnham, Kevin J
Trehalose elevates brain zinc levels following controlled cortical impact in a mouse model of traumatic brain injury
Metallomics
Volume: 10
Page(s): 846-853
Year: 2018
Author(s): Portbury, Stuart D., Hare, Dominic J., Bishop, David P., Finkelstein, David I., Doble, Philip A., Adlard, Paul A.
Author(s): Portbury, Stuart D., Hare, Dominic J., Bishop, David P., Finkelstein, David I., Doble, Philip A., Adlard, Paul A.
Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species
PLOS Pathogens
Year: 08/08/2018
Author(s): Simote Totauhelotu Foliaki, David Westaway, Victoria Lewis, David Isaac Finkelstein, Victoria Lawson, Harold Arthur Coleman, Matteo Senesi, Abu Mohammed Taufiqual Islam, Feng Chen, Shannon Sarros, Blaine Roberts, Paul Anthony Adlard, Steven John Collins
Author(s): Simote Totauhelotu Foliaki, David Westaway, Victoria Lewis, David Isaac Finkelstein, Victoria Lawson, Harold Arthur Coleman, Matteo Senesi, Abu Mohammed Taufiqual Islam, Feng Chen, Shannon Sarros, Blaine Roberts, Paul Anthony Adlard, Steven John Collins
Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc
PLOS Pathogens
Year: 10/04/2019
Author(s): Simote Totauhelotu Foliaki, David Westaway, Victoria Lewis, Abu Mohammed Taufiqual Islam, Laura Jane Ellett, Matteo Senesi, David Isaac Finkelstein, Blaine Roberts, Victoria A. Lawson, Paul Anthony Adlard, Steven John Collins
Author(s): Simote Totauhelotu Foliaki, David Westaway, Victoria Lewis, Abu Mohammed Taufiqual Islam, Laura Jane Ellett, Matteo Senesi, David Isaac Finkelstein, Blaine Roberts, Victoria A. Lawson, Paul Anthony Adlard, Steven John Collins
Metal chaperones: a novel therapeutic strategy for brain injury?
Brain injury
Year: 03/12/2018
Targeting metals rescues the phenotype in an animal model of tauopathy.
Metallomics : integrated biometal science
Year: 01/09/2018
The Down Syndrome-Associated Protein, Regulator of Calcineurin-1, is Altered in Alzheimer's Disease and Dementia with Lewy Bodies.
Journal of Alzheimer's disease & Parkinsonism
Year: 06/03/2019
Ferroptosis and cell death mechanisms in Parkinson's disease
Neurochem Int
Volume: 104
Page(s): 34-48
Year: 2017
Author(s): Guiney, S. J., Adlard, P. A., Bush, A. I., Finkelstein, D. I., Ayton, S.
Author(s): Guiney, S. J., Adlard, P. A., Bush, A. I., Finkelstein, D. I., Ayton, S.
Lithium suppression of tau induces brain iron accumulation and neurodegeneration
Mol Psychiatry
Volume: 22
Page(s): 396-406
Year: 2017
Author(s): Lei, P., Ayton, S., Appukuttan, A. T., Moon, S., Duce, J. A., Volitakis, I., Cherny, R., Wood, S. J., Greenough, M., Berger, G., Pantelis, C., McGorry, P., Yung, A., Finkelstein, D. I., Bush, A. I.
Author(s): Lei, P., Ayton, S., Appukuttan, A. T., Moon, S., Duce, J. A., Volitakis, I., Cherny, R., Wood, S. J., Greenough, M., Berger, G., Pantelis, C., McGorry, P., Yung, A., Finkelstein, D. I., Bush, A. I.
Pramipexole restores depressed transmission in the ventral hippocampus following MPTP-lesion
Sci Rep
Volume: 7
Page(s): 44426
Year: 2017
Author(s): Castro-Hernández, J., Adlard, P. A., Finkelstein, D. I.
Author(s): Castro-Hernández, J., Adlard, P. A., Finkelstein, D. I.
Excessive early-life dietary exposure: a potential source of elevated brain iron and a risk factor for Parkinson’s disease
npj Parkinson's Disease
Volume: 3
Page(s): 1
Year: 2017
In vivo prion models and the disconnection between transmissibility and neurotoxicity
Ageing Res Rev
Volume: 36
Page(s): 156-164
Year: 2017
The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's disease
Acta Neuropathol Commun
Volume: 5
Page(s): 53
Year: 2017
A time-course analysis of changes in cerebral metal levels following a controlled cortical impact
Metallomics
Volume: 8
Page(s): 193-200
Year: 2016
Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimer's Disease
J Alzheimers Dis
Year: 2017
Author(s): Portbury, S. D., Hare, D. J., Sgambelloni, C., Perronnes, K., Portbury, A. J., Finkelstein, D. I., Adlard, P. A.
Author(s): Portbury, S. D., Hare, D. J., Sgambelloni, C., Perronnes, K., Portbury, A. J., Finkelstein, D. I., Adlard, P. A.
Trehalose improves traumatic brain injury-induced cognitive impairment
PLoS One
Volume: 12
Page(s): e0183683
Year: 2017
Author(s): Portbury, S. D., Hare, D. J., Finkelstein, D. I., Adlard, P. A.
Author(s): Portbury, S. D., Hare, D. J., Finkelstein, D. I., Adlard, P. A.
Type-1 interferons contribute to the neuroinflammatory response and disease progression of the MPTP mouse model of Parkinson's disease.
Glia
Year: 07/2016
Author(s): Main BS, Zhang M, Brody KM, Ayton S, Frugier T, Steer D, Finkelstein D, Crack PJ, Taylor JM
Author(s): Main BS, Zhang M, Brody KM, Ayton S, Frugier T, Steer D, Finkelstein D, Crack PJ, Taylor JM
Pathogenic mechanisms of prion protein, amyloid-beta and alpha-synuclein misfolding: the prion concept and neurotoxicity of protein oligomers
J Neurochem
Volume: 139
Page(s): 162-180
Year: 2016
N-acetylcysteine modulates glutamatergic dysfunction and depressive behavior in Huntington's disease
Hum Mol Genet
Volume: 25
Page(s): 2923-2933
Year: 2016
Transferrin protects against Parkinsonian neurotoxicity and is deficient in Parkinson’s substantia nigra
Signal Transduction and Targeted Therapy
Volume: 1
Page(s): 16015
Year: 2016
Implantable amyloid hydrogels for promoting stem cell differentiation to neurons
NPG Asia Materials
Volume: 8
Page(s): e304
Year: 2016
Effects of Neonatal Iron Feeding and Chronic Clioquinol Administration on the Parkinsonian Human A53T Transgenic Mouse
ACS Chem Neurosci
Volume: 7
Page(s): 360-6
Year: 2016
Restoration of intestinal function in an MPTP model of Parkinson's Disease
Sci Rep
Volume: 6
Page(s): 30269
Year: 2016
Clioquinol Improves Cognitive, Motor Function, and Microanatomy of the Alpha-Synuclein hA53T Transgenic Mice
ACS Chem Neurosci
Volume: 7
Page(s): 119-29
Year: 2016
Graphene Functionalized Scaffolds Reduce the Inflammatory Response and Supports Endogenous Neuroblast Migration when Implanted in the Adult Brain
PLoS One
Volume: 11
Page(s): e0151589
Year: 2016
Metals in Alzheimer's and Parkinson's Disease: Relevance to Dementia with Lewy Bodies
J Mol Neurosci
Volume: 60
Page(s): 279-288
Year: 2016
Iron Regulates Apolipoprotein E Expression and Secretion in Neurons and Astrocytes
J Alzheimers Dis
Volume: 51
Page(s): 471-87
Year: 2016
Serotonergic markers in Parkinson's disease and levodopa-induced dyskinesias
Mov Disord
Volume: 30
Page(s): 796-804
Year: 2015
Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse
Neurobiol Dis
Volume: 81
Page(s): 168-75
Year: 2015
High order W02-reactive stable oligomers of amyloid-beta are produced in vivo and in vitro via dialysis and filtration of synthetic amyloid-beta monomer
J Alzheimers Dis
Volume: 44
Page(s): 69-78
Year: 2015
Parkinson's disease iron deposition caused by nitric oxide-induced loss of beta-amyloid precursor protein
J Neurosci
Volume: 35
Page(s): 3591-7
Year: 2015
GSK-3beta dysregulation contributes to parkinson's-like pathophysiology with associated region-specific phosphorylation and accumulation of tau and alpha-synuclein
Cell Death Differ
Volume: 22
Page(s): 838-51
Year: 2015
Comparative Study of Metal Quantification in Neurological Tissue Using Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry Imaging and X-ray Fluorescence Microscopy
Anal Chem
Volume: 87
Page(s): 6639-45
Year: 2015
Is early-life iron exposure critical in neurodegeneration?
Nat Rev Neurol
Volume: 11
Page(s): 536-44
Year: 2015
Isoflurane in the Aged Brain: A Link to Altered Amyloid Precursor Protein Processing
Journal of Parkinson’s disease & Alzheimer’s disease
Volume: 2
Page(s): 8-10
Year: 2015
Enduring Elevations of Hippocampal Amyloid Precursor Protein and Iron Are Features of beta-Amyloid Toxicity and Are Mediated by Tau
Neurotherapeutics
Volume: 12
Page(s): 862-73
Year: 2015
Cell infiltration into a 3D electrospun fiber and hydrogel hybrid scaffold implanted in the brain
Biomatter
Volume: 5
Page(s): e1005527
Year: 2015
A novel approach to rapidly prevent age-related cognitive decline
Aging Cell
Volume: 13
Page(s): 351-359
Year: 2014
Author(s): Adlard, Paul A., Sedjahtera, Amelia, Gunawan, Lydia, Bray, Lisa, Hare, Dominic, Lear, Jessica, Doble, Philip, Bush, Ashley I., Finkelstein, David I., Cherny, Robert A.
Author(s): Adlard, Paul A., Sedjahtera, Amelia, Gunawan, Lydia, Bray, Lisa, Hare, Dominic, Lear, Jessica, Doble, Philip, Bush, Ashley I., Finkelstein, David I., Cherny, Robert A.
Glia and zinc in ageing and Alzheimer's disease: a mechanism for cognitive decline?
Front Aging Neurosci
Volume: 6
Page(s): 137
Year: 2014
Author(s): Hancock, S. M., Finkelstein, D. I., Adlard, P. A.
Author(s): Hancock, S. M., Finkelstein, D. I., Adlard, P. A.
An iron--dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta
Chemical Science
Volume: 5
Page(s): 2160--2169
Year: 2014
Effects of GDNF-Loaded Injectable Gelatin-Based Hydrogels on Endogenous Neural Progenitor Cell Migration
Advanced healthcare materials
Volume: 3
Page(s): 761--774
Year: 2014
Increased Ndfip1 in the substantia nigra of Parkinsonian Brains is associated with elevated Iron levels
Year: 2014
EVIDENCE FOR APOE PROTECTING AGAINST BRAIN IRON OVERLOAD
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume: 4
Page(s): P878
Year: 2014
Glia and zinc in ageing and Alzheimer’s disease: a mechanism for cognitive decline?
Frontiers in aging neuroscience
Volume: 6
Year: 2014
A review of $β$-amyloid neuroimaging in Alzheimer's disease
Frontiers in neuroscience
Volume: 8
Year: 2014
Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging
Chem. Sci.
Volume: 6
Page(s): 5383-5393
Year: 2015
Zinc affects the proteolytic stability of Apolipoprotein E in an isoform-dependent way
Neurobiol Dis
Volume: 81
Page(s): 38-48
Year: 2015
Interactions of metals and Apolipoprotein E in Alzheimer's disease
Front Aging Neurosci
Volume: 6
Page(s): 121
Year: 2014
Author(s): Xu, H., Finkelstein, D. I., Adlard, P. A.
Author(s): Xu, H., Finkelstein, D. I., Adlard, P. A.
Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson's disease
Molecular Neurodegeneration
Volume: 9
Page(s): 27
Year: 2014
Author(s): Ayton, S., Lei, P., Adlard, P. A., Volitakis, I., Cherny, R. A., Bush, A. I., Finkelstein, D. I.
Author(s): Ayton, S., Lei, P., Adlard, P. A., Volitakis, I., Cherny, R. A., Bush, A. I., Finkelstein, D. I.
Motor and cognitive deficits in aged tau knockout mice in two background strains
Molecular Neurodegeneration
Volume: 9
Page(s): 29
Year: 2014
Author(s): Lei, P., Ayton, S., Moon, S., Zhang, Q., Volitakis, I., Finkelstein, D. I., Bush, A. I.
Author(s): Lei, P., Ayton, S., Moon, S., Zhang, Q., Volitakis, I., Finkelstein, D. I., Bush, A. I.
Rescue of the Friedreich Ataxia Knockout Mutation in Transgenic Mice Containing an FXN-EGFP Genomic Reporter
PLoS One
Volume: 9
Page(s): e93307
Year: 2014
Author(s): Sarsero, J. P., Holloway, T. P., Li, L., Finkelstein, D. I., Ioannou, P. A.
Author(s): Sarsero, J. P., Holloway, T. P., Li, L., Finkelstein, D. I., Ioannou, P. A.
Role of metal ions in the cognitive decline of Down syndrome
Frontiers in Aging Neuroscience
Volume: 6
Page(s): 136
Year: 2014
Author(s): Malakooti, N., Pritchard, M. A., Adlard, P. A., Finkelstein, D. I.
Author(s): Malakooti, N., Pritchard, M. A., Adlard, P. A., Finkelstein, D. I.
Nanofibrous scaffolds releasing a small molecule BDNF-mimetic for the re-direction of endogenous neuroblast migration in the brain
Biomaterials
Volume: 35
Page(s): 2692--2712
Year: 2014
PROTEIN AND METAL ALTERATIONS IN PLATELETS OF ALZHEIMER'S DISEASE PATIENTS
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume: 10
Page(s): P518
Year: 2014
Neuronal iron is regulated by tau-mediated APP trafficking: Implications in Alzheimer's disease and Parkinson's disease
JOURNAL OF NEUROCHEMISTRY
Volume: 130
Page(s): 33--33
Year: 2014
REVISITING THE ALZHEIMER'S AND PARKINSONISM PHENOTYPES OF TAU KO MICE: POTENTIAL GENETIC BACKGROUND EFFECT
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume: 10
Page(s): P924
Year: 2014
Metal chaperones prevent zinc-mediated cognitive decline
Neurobiology of disease
Year: 2014
Age-Dependent Effects of A53T Alpha-Synuclein on Behavior and Dopaminergic Function
PLoS One
Volume: 8
Page(s): e60378
Year: 2013
Author(s): Oaks, Adam W., Frankfurt, Maya, Finkelstein, David I., Sidhu, Anita
Author(s): Oaks, Adam W., Frankfurt, Maya, Finkelstein, David I., Sidhu, Anita
Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease
Annals of Neurology
Volume: 73
Page(s): 554-9
Year: 2013
Author(s): Ayton, S., Lei, P., Duce, J. A., Wong, B. X., Sedjahtera, A., Adlard, P. A., Bush, A. I., Finkelstein, D. I.
Author(s): Ayton, S., Lei, P., Duce, J. A., Wong, B. X., Sedjahtera, A., Adlard, P. A., Bush, A. I., Finkelstein, D. I.
Amine oxidase activity of $β$-amyloid precursor protein modulates systemic and local catecholamine levels
Molecular psychiatry
Volume: 18
Page(s): 245--254
Year: 2013
Intravenous immunglobulin binds beta amyloid and modifies its aggregation, neurotoxicity and microglial phagocytosis in vitro
Year: 2013
A NOVEL RELATIONSHIP BETWEEN beta-AMYLOID PROTEIN PRECURSOR AND TAU IN ALZHEIMER'S DISEASE RELATED IRON DISRUPTION
AMERICAN JOURNAL OF HEMATOLOGY
Volume: 88
Page(s): E34--E35
Year: 2013
Clioquinol synergistically augments rescue by zinc supplementation in a mouse model of acrodermatitis enteropathica
PloS one
Volume: 8
Page(s): e72543
Year: 2013
Stereotaxic delivery of M1000 prions to the CA1 hippocampal region of wild type mice induces acute transient ethological and memory disturbance
PRION
Volume: 8
Page(s): 91--91
Year: 2014
Therapeutic protein supplementation corrects iron export fatigue in Parkinson's disease
MOVEMENT DISORDERS
Volume: 29
Page(s): S134--S134
Year: 2014
ZINC AFFECTS THE STABILITY OF APOLIPOPROTEIN E IN ALZHEIMER'S DISEASE
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume: 10
Page(s): P877
Year: 2014
The effect of paraformaldehyde fixation and sucrose cryoprotection on metal concentration in murine neurological tissue (vol 29, pg 565, 2014)
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
Volume: 29
Page(s): 1726--1726
Year: 2014
Metallobiology of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
Metallomics
Volume: 5
Page(s): 91-109
Year: 2013
Author(s): Hare, D. J., Adlard, P. A., Doble, P. A., Finkelstein, D. I.
Author(s): Hare, D. J., Adlard, P. A., Doble, P. A., Finkelstein, D. I.
The effect of dopamine on MPTP-induced rotarod disability
Neuroscience Letters
Volume: 543
Page(s): 105-9
Year: 2013
Author(s): Ayton, S., George, J. L., Adlard, P. A., Bush, A. I., Cherny, R. A., Finkelstein, D. I.
Author(s): Ayton, S., George, J. L., Adlard, P. A., Bush, A. I., Cherny, R. A., Finkelstein, D. I.
High-resolution elemental bioimaging of Ca, Mn, Fe, Co, Cu, and Zn employing LA-ICP-MS and hydrogen reaction gas
Analytical chemistry
Volume: 84
Page(s): 6707--6714
Year: 2012
Serotonin dysfunction in Parkinson's disease does not correlate with levodopa-induced dyskinesias
MOVEMENT DISORDERS
Volume: 28
Page(s): S366--S366
Year: 2013
The Role of the Plasma Membrane Redox System in the Pathogenesis of Alzheimer’s Disease
Studies on Alzheimer's Disease
Page(s): 55--69
Year: 2013
The neuroinflammatory response induced by MPTP is altered in mice lacking the type-I interferon-alpha receptor-1 (IFNAR1)
MOVEMENT DISORDERS
Volume: 28
Page(s): S367--S367
Year: 2013
PBT434, a novel 8-hydroxyquinazolinone, preserves nigro-striatal circuitry, improves motor performance and inhibits alpha synuclein accumulation in animal models of Parkinson's disease by modulation of iron homeostasis
MOVEMENT DISORDERS
Volume: 28
Page(s): S369--S369
Year: 2013
Rescue of Behavioral and neurodegenerative phenotypes in symptomatic tau KO mice: Therapeutic implications for neurodegenerative diseases
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume: 9
Page(s): P848
Year: 2013
Zinc in Alzheimer’s and Parkinson’s Diseases
Encyclopedia of Metalloproteins
Page(s): 2433--2441
Year: 2013
Loss of tau induces age-dependent anaemia with reduced longevity in mice
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume: 9
Page(s): P716
Year: 2013
Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export
Nature Medicine
Volume: 18
Page(s): 291-5
Year: 2012
Author(s): Lei, P., Ayton, S., Finkelstein, D. I., Spoerri, L., Ciccotosto, G. D., Wright, D. K., Wong, B. X., Adlard, P. A., Cherny, R. A., Lam, L. Q., Roberts, B. R., Volitakis, I., Egan, G. F., McLean, C. A., Cappai, R., Duce, J. A., Bush, A. I.
Author(s): Lei, P., Ayton, S., Finkelstein, D. I., Spoerri, L., Ciccotosto, G. D., Wright, D. K., Wong, B. X., Adlard, P. A., Cherny, R. A., Lam, L. Q., Roberts, B. R., Volitakis, I., Egan, G. F., McLean, C. A., Cappai, R., Duce, J. A., Bush, A. I.
The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease
The Journal of Experimental Medicine
Volume: 209
Page(s): 837-54
Year: 2012
Author(s): Hung, L. W., Villemagne, V. L., Cheng, L., Sherratt, N. A., Ayton, S., White, A. R., Crouch, P. J., Lim, S., Leong, S. L., Wilkins, S., George, J., Roberts, B. R., Pham, C. L., Liu, X., Chiu, F. C., Shackleford, D. M., Powell, A. K., Masters, C. L., Bush, A. I., O'Keefe, G., Culvenor, J. G., Cappai, R., Cherny, R. A., Donnelly, P. S., Hill, A. F., Finkelstein, D. I., Barnham, K. J.
Author(s): Hung, L. W., Villemagne, V. L., Cheng, L., Sherratt, N. A., Ayton, S., White, A. R., Crouch, P. J., Lim, S., Leong, S. L., Wilkins, S., George, J., Roberts, B. R., Pham, C. L., Liu, X., Chiu, F. C., Shackleford, D. M., Powell, A. K., Masters, C. L., Bush, A. I., O'Keefe, G., Culvenor, J. G., Cappai, R., Cherny, R. A., Donnelly, P. S., Hill, A. F., Finkelstein, D. I., Barnham, K. J.
Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model
The Journal of Biological Chemistry
Volume: 286
Page(s): 44035-44
Year: 2011
Author(s): Soon, C. P., Donnelly, P. S., Turner, B. J., Hung, L. W., Crouch, P. J., Sherratt, N. A., Tan, J. L., Lim, N. K., Lam, L., Bica, L., Lim, S., Hickey, J. L., Morizzi, J., Powell, A., Finkelstein, D. I., Culvenor, J. G., Masters, C. L., Duce, J., White, A. R., Barnham, K. J., Li, Q. X.
Author(s): Soon, C. P., Donnelly, P. S., Turner, B. J., Hung, L. W., Crouch, P. J., Sherratt, N. A., Tan, J. L., Lim, N. K., Lam, L., Bica, L., Lim, S., Hickey, J. L., Morizzi, J., Powell, A., Finkelstein, D. I., Culvenor, J. G., Masters, C. L., Duce, J., White, A. R., Barnham, K. J., Li, Q. X.
Improving acquisition times of elemental bio-imaging for quadrupole-based LA-ICP-MS
J. Anal. At. Spectrom.
Year: 2011
Characterising the interaction between tau and metals in rTg4510 mice
Alzheimer's & Dementia
Volume: 7
Page(s): S479--S480
Year: 2011
Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory
Human molecular genetics
Year: 2012
Three-dimensional atlas of iron, copper, and zinc in the mouse cerebrum and brainstem
Analytical chemistry
Volume: 84
Page(s): 3990--3997
Year: 2012
PBT2 Reduces Toxicity in a C. elegans Model of polyQ Aggregation and Extends Lifespan, Reduces Striatal Atrophy and Improves Motor Performance in the R6/2 Mouse Model of Huntington's Disease.
Journal of Huntington's disease
Volume: 1
Page(s): 211--219
Year: 2012
Method to impart electro-and biofunctionality to neural scaffolds using graphene--polyelectrolyte multilayers
ACS applied materials & interfaces
Volume: 4
Page(s): 4524--4531
Year: 2012
Type-I interferon signaling is pro-inflammatory in models of Parkinson's disease
JOURNAL OF NEUROIMMUNOLOGY
Volume: 253
Page(s): 118--118
Year: 2012
Cognitive loss in zinc transporter-3 knock-out mice: a phenocopy for the synaptic and memory deficits of Alzheimer's disease?
Journal of Neuroscience
Volume: 30
Page(s): 1631-6
Year: 2010
Author(s): Adlard, P. A., Parncutt, J. M., Finkelstein, D. I., Bush, A. I.
Author(s): Adlard, P. A., Parncutt, J. M., Finkelstein, D. I., Bush, A. I.
Implantation of functionalised thermally gelling xyloglucan hydrogel within the brain: Associated neurite infiltration and inflammatory response
Tissue engineering, Part A
Volume: 16
Page(s): 2833-2842
Year: 2010
Author(s): Nisbet, D. R., Rodda, A. E., Horne, M. K., Forsythe, J. S., Finkelstein, D. I.
Author(s): Nisbet, D. R., Rodda, A. E., Horne, M. K., Forsythe, J. S., Finkelstein, D. I.
Novel Metal Ligands Prevent Neuronal Loss and Motor Deficits in Wild Type and Alpha-synuclein Transgenic Mice Treated with 6-Hydroxydopamine Or MPTP
Movement Disorders
Volume: 25
Page(s): S665-S666
Year: 2010
Author(s): Cherny, R. A., George, J. L., Gunawan, L., Critch, N., Cortes, M., Liu, X., Nurjono, M., Laughton, K., Volitakis, I., Parsons, J., Barnham, K. J., Gautier, E., Bush, A. I., Finkelstein, D. I.
Author(s): Cherny, R. A., George, J. L., Gunawan, L., Critch, N., Cortes, M., Liu, X., Nurjono, M., Laughton, K., Volitakis, I., Parsons, J., Barnham, K. J., Gautier, E., Bush, A. I., Finkelstein, D. I.
Tau protein: relevance to Parkinson's disease
The International Journal of Biochemistry & Cell Biology
Volume: 42
Page(s): 1775-8
Year: 2010
Author(s): Lei, P., Ayton, S., Finkelstein, D. I., Adlard, P. A., Masters, C. L., Bush, A. I.
Author(s): Lei, P., Ayton, S., Finkelstein, D. I., Adlard, P. A., Masters, C. L., Bush, A. I.
Three-dimensional elemental bio-imaging of Fe, Zn, Cu, Mn and P in a 6-hydroxydopamine lesioned mouse brain
Metallomics
Volume: 2
Page(s): 745-53
Year: 2010
Author(s): Hare, D. J., George, J. L., Grimm, R., Wilkins, S., Adlard, P. A., Cherny, R. A., Bush, A. I., Finkelstein*, D. I., Doble, P.
Author(s): Hare, D. J., George, J. L., Grimm, R., Wilkins, S., Adlard, P. A., Cherny, R. A., Bush, A. I., Finkelstein*, D. I., Doble, P.
Metal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's disease
PloS one
Volume: 6
Page(s): e17669
Year: 2011
The Alzheimer's therapeutic PBT2 achieves cognitive benefit by combining neuroprotection with neurorestoration: studies in animal models of Alzheimer's disease and Huntington's disease
Alzheimer's & Dementia
Volume: 7
Page(s): S457
Year: 2011
The relationship between beta-amyloid protein precursor and tau in Alzheimer's disease-related iron disruption
Alzheimer's & Dementia
Volume: 7
Page(s): S509
Year: 2011
Loss of tau induces age-dependent neurodegeneration
Alzheimer's & Dementia
Volume: 7
Page(s): e6
Year: 2011
Inhibition of $α$-synuclein Aggregation Leads to Therapeutic Benefits in Multiple Animal Models of Parkinson'S Disease.
Alzheimer's & Dementia
Volume: 6
Page(s): e62--e63
Year: 2010
alpha-synuclein transgenic mice reveal compensatory increases in Parkinson's disease-associated proteins DJ-1 and Parkin and have enhanced alpha-synuclein and PINK1 levels after rotenone treatment
Journal of Molecular Neuroscience
Volume: 42
Page(s): 243-54
Year: 2010
Author(s): George, S., Mok, S. S., Nurjono, M., Ayton, S., Finkelstein, D. I., Masters, C. L., Li, Q. X., Culvenor, J. G.
Author(s): George, S., Mok, S. S., Nurjono, M., Ayton, S., Finkelstein, D. I., Masters, C. L., Li, Q. X., Culvenor, J. G.
Enhancing neurite outgrowth from primary neurones and neural stem cells using thermoresponsive hydrogel scaffolds for the repair of spinal cord injury
Journal of Biomedical Materials Research A
Volume: 89
Page(s): 24-35
Year: 2009
Author(s): Nisbet, D. R., Moses, D., Gengenbach, T. R., Forsythe, J. S., Finkelstein, D. I., Horne, M. K.
Author(s): Nisbet, D. R., Moses, D., Gengenbach, T. R., Forsythe, J. S., Finkelstein, D. I., Horne, M. K.
Neural Tissue Engineering of the CNS Using Hydrogels - A review (vol 5, pg 293, 2003)
Journal of Biomedical Materials Research Part B-Applied Biomaterials
Volume: 88B
Page(s): 304
Year: 2009
Author(s): Nisbet, D. R., Crompton, K. E., Horne, M. K., Finkelstein, D. I., Forsythe, J. S.
Author(s): Nisbet, D. R., Crompton, K. E., Horne, M. K., Finkelstein, D. I., Forsythe, J. S.
Neurite infiltration and cellular response to electrospun polycaprolactone scaffolds implanted into the brain
Biomaterials
Volume: 30
Page(s): 4573-80
Year: 2009
Author(s): Nisbet, D. R., Rodda, A. E., Horne, M. K., Forsythe, J. S., Finkelstein, D. I.
Author(s): Nisbet, D. R., Rodda, A. E., Horne, M. K., Forsythe, J. S., Finkelstein, D. I.
Dopamine D2 receptor knockout mice develop features of Parkinson disease
Annals of neurology
Volume: 66
Page(s): 472--484
Year: 2009
Effect of unilateral lesion of the nigrostriatal dopamine pathway on survival and neurochemistry of parafascicular nucleus neurons in the rat—evaluation of time-course and LGR8 expression
Brain research
Volume: 1271
Page(s): 83--94
Year: 2009
Altered fast-and slow-twitch muscle fibre characteristics in female mice with a (S248F) knock-in mutation of the brain neuronal nicotinic acetylcholine receptor
Journal of muscle research and cell motility
Volume: 30
Page(s): 73--83
Year: 2009
Clioquinol Protects Against Cell Death in Parkinson’s Disease Models In Vivo and In Vitro
The Basal Ganglia IX
Page(s): 431--442
Year: 2009
Molecular level and microstructural characterisation of thermally sensitive chitosan hydrogels
Soft Matter
Volume: 5
Page(s): 4704--4711
Year: 2009
P1. 050 Novel neuroprotective agents for the treatment of Parkinson's disease
Parkinsonism & Related Disorders
Volume: 15
Page(s): S41--S42
Year: 2009
Review paper: a review of the cellular response on electrospun nanofibers for tissue engineering
Journal of biomaterials applications
Volume: 24
Page(s): 7-29
Year: 2009
Author(s): Nisbet, D. R., Forsythe, J. S., Shen, W., Finkelstein, D. I., Horne, M. K.
Author(s): Nisbet, D. R., Forsythe, J. S., Shen, W., Finkelstein, D. I., Horne, M. K.
Surface and bulk characterisation of electrospun membranes: problems and improvements
Colloids Surf B Biointerfaces
Volume: 71
Page(s): 1-12
Year: 2009
Author(s): Nisbet, D. R., Rodda, A. E., Finkelstein, D. I., Horne, M. K., Forsythe, J. S., Shen, W.
Author(s): Nisbet, D. R., Rodda, A. E., Finkelstein, D. I., Horne, M. K., Forsythe, J. S., Shen, W.
Targeting the Progression of Parkinson's Disease
Current Neuropharmacology
Volume: 7
Page(s): 9-36
Year: 2009
Author(s): George, J. L., Mok, S., Moses, D., Wilkins, S., Bush, A. I., Cherny, R. A., Finkelstein, D. I.
Author(s): George, J. L., Mok, S., Moses, D., Wilkins, S., Bush, A. I., Cherny, R. A., Finkelstein, D. I.
Estrogen enhances the number of nigral dopaminergic neurons of adult male mice without affecting nigral neuroglial number and morphology
Neuroscience letters
Volume: 435
Page(s): 210-4
Year: 2008
Author(s): Tripanichkul, W., Jaroensuppaperch, E. O., Finkelstein, D. I.
Author(s): Tripanichkul, W., Jaroensuppaperch, E. O., Finkelstein, D. I.
Fetal striatum- and ventral mesencephalon-derived expanded neurospheres rescue dopaminergic neurons in vitro and the nigro-striatal system in vivo
Neuroscience
Volume: 154
Page(s): 606-20
Year: 2008
Author(s): Moses, D., Drago, J., Teper, Y., Gantois, I., Finkelstein, D. I., Horne, M. K.
Author(s): Moses, D., Drago, J., Teper, Y., Gantois, I., Finkelstein, D. I., Horne, M. K.
Relaxin family peptides and receptors in mammalian brain
Annals of the New York Academy of Sciences
Volume: 1160
Page(s): 226--235
Year: 2009
Pbt2 for Pre-dementia Alzheimer's Disease: Animal and Clinical Evidence
Alzheimer's & Dementia
Volume: 5
Page(s): e5
Year: 2009
P2. 097 A reactive nitrogen species scavenger is neuroprotective in multiple Parkinson's disease animal models
Parkinsonism & Related Disorders
Volume: 15
Page(s): S115
Year: 2009
Relaxin Family Peptides and Receptors
Relaxin and Related Peptides: Fifth International Conference
Page(s): 226
Year: 2009
The basal ganglia IX
Volume: 58
Year: 2009
Leucine-rich repeat-containing G-protein-coupled receptor 8 in the rat brain: Enrichment in thalamic neurons and their efferent projections
Neuroscience
Volume: 156
Page(s): 319-33
Year: 2008
Author(s): Sedaghat, K., Shen, P. J., Finkelstein, D. I., Henderson, J. M., Gundlach, A. L.
Author(s): Sedaghat, K., Shen, P. J., Finkelstein, D. I., Henderson, J. M., Gundlach, A. L.
Mice deficient for the chromosome 21 ortholog Itsn1 exhibit vesicle-trafficking abnormalities
Hum Mol Genet
Volume: 17
Page(s): 3281-90
Year: 2008
Author(s): Yu, Y., Chu, P. Y., Bowser, D. N., Keating, D. J., Dubach, D., Harper, I., Tkalcevic, J., Finkelstein, D. I., Pritchard, M. A.
Author(s): Yu, Y., Chu, P. Y., Bowser, D. N., Keating, D. J., Dubach, D., Harper, I., Tkalcevic, J., Finkelstein, D. I., Pritchard, M. A.
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta
Neuron
Volume: 59
Page(s): 43-55
Year: 2008
Author(s): Adlard, P. A., Cherny, R. A., Finkelstein, D. I., Gautier, E., Robb, E., Cortes, M., Volitakis, I., Liu, X., Smith, J. P., Perez, K., Laughton, K., Li, Q. X., Charman, S. A., Nicolazzo, J. A., Wilkins, S., Deleva, K., Lynch, T., Kok, G., Ritchie, C. W., Tanzi, R. E., Cappai, R., Masters, C. L., Barnham, K. J., Bush, A. I.
Author(s): Adlard, P. A., Cherny, R. A., Finkelstein, D. I., Gautier, E., Robb, E., Cortes, M., Volitakis, I., Liu, X., Smith, J. P., Perez, K., Laughton, K., Li, Q. X., Charman, S. A., Nicolazzo, J. A., Wilkins, S., Deleva, K., Lynch, T., Kok, G., Ritchie, C. W., Tanzi, R. E., Cappai, R., Masters, C. L., Barnham, K. J., Bush, A. I.
17beta-Estradiol reduces nitrotyrosine immunoreactivity and increases SOD1 and SOD2 immunoreactivity in nigral neurons in male mice following MPTP insult
Brain Research
Volume: 1164
Page(s): 24-31
Year: 2007
Author(s): Tripanichkul, W., Sripanichkulchai, K., Duce, J. A., Finkelstein, D. I.
Author(s): Tripanichkul, W., Sripanichkulchai, K., Duce, J. A., Finkelstein, D. I.
Neural tissue engineering of the CNS using hydrogels
Journal of Biomedical Materials Research Part B-Applied Biomaterials
Volume: 87
Page(s): 251-63
Year: 2008
Author(s): Nisbet, D. R., Crompton, K. E., Horne, M. K., Finkelstein, D. I., Forsythe, J. S.
Author(s): Nisbet, D. R., Crompton, K. E., Horne, M. K., Finkelstein, D. I., Forsythe, J. S.
Sprouting of dopamine terminals and altered dopamine release and uptake in Parkinsonian dyskinaesia
Brain
Volume: 131
Page(s): 1574-87
Year: 2008
Author(s): Lee, J., Zhu, W. M., Stanic, D., Finkelstein, D. I., Horne, M. H., Henderson, J., Lawrence, A. J., O'Connor, L., Tomas, D., Drago, J., Horne, M. K.
Author(s): Lee, J., Zhu, W. M., Stanic, D., Finkelstein, D. I., Horne, M. H., Henderson, J., Lawrence, A. J., O'Connor, L., Tomas, D., Drago, J., Horne, M. K.
Interaction of embryonic cortical neurons on nanofibrous scaffolds for neural tissue engineering
Journal of Neural Engineering
Volume: 4
Page(s): 35-41
Year: 2007
Author(s): Nisbet, D. R., Pattanawong, S., Ritchie, N.E.., Shen, W., Finkelstein, D. I., Horne, M. K., Forsythe, J. S.
Author(s): Nisbet, D. R., Pattanawong, S., Ritchie, N.E.., Shen, W., Finkelstein, D. I., Horne, M. K., Forsythe, J. S.
Quantitative elemental bio-imaging of Mn, Fe, Cu and Zn in 6-hydroxydopamine induced Parkinsonism mouse models
Metallomics
Volume: 1
Page(s): 53--58
Year: 2008
O3-05-04: The 8-hydroxyquinoline analog PBT2 rapidly restores cognition and reduces soluble Abeta in Alzheimer transgenic mice
Alzheimer's & Dementia
Volume: 4
Page(s): T169
Year: 2008
Metals, Oxidative Stress, and Brain Biology
Encyclopedia of Stress (Second Edition); Bruce M, Kloet ER, de Robert R, et al., Eds
Page(s): 724--6
Year: 2007
Polylysine-functionalised thermoresponsive chitosan hydrogel for neural tissue engineering
Biomaterials
Volume: 28
Page(s): 441-9
Year: 2007
Author(s): Crompton, K. E., Goud, J. D., Bellamkonda, R. V., Gengenbach, T. R., Finkelstein, D. I., Horne, M. K., Forsythe, J. S.
Author(s): Crompton, K. E., Goud, J. D., Bellamkonda, R. V., Gengenbach, T. R., Finkelstein, D. I., Horne, M. K., Forsythe, J. S.
Inflammatory response on injection of chitosan/GP to the brain
Journal of Materials Science: Materials in Medicine
Volume: 17
Page(s): 633-9
Year: 2006
Author(s): Crompton, K. E., Tomas, D., Finkelstein, D. I., Marr, M., Forsythe, J. S., Horne, M. K.
Author(s): Crompton, K. E., Tomas, D., Finkelstein, D. I., Marr, M., Forsythe, J. S., Horne, M. K.
Morphology and gelation of thermosensitive xyloglucan hydrogels
Biophysical Chemistry
Volume: 121
Page(s): 14-20
Year: 2006
Author(s): Nisbet, D. R., Crompton, K. E., Hamilton, S. D., Shirakawa, S., Prankerd, R. J., Finkelstein, D. I., Horne, M. K., Forsythe, J. S.
Author(s): Nisbet, D. R., Crompton, K. E., Hamilton, S. D., Shirakawa, S., Prankerd, R. J., Finkelstein, D. I., Horne, M. K., Forsythe, J. S.
The effect of surface hydrophilicity on the behavior of embryonic cortical neurons
Journal of Colloid and Interface Science
Volume: 299
Page(s): 647-55
Year: 2006
Author(s): Nisbet, D. R., Pattanawong, S., Nunan, J., Shen, W., Horne, M. K., Finkelstein, D. I., Forsythe, J. S.
Author(s): Nisbet, D. R., Pattanawong, S., Nunan, J., Shen, W., Horne, M. K., Finkelstein, D. I., Forsythe, J. S.
Alterations in the proportions of skeletal muscle proteins following a unilateral lesion to the substantia nigra pars compacta of rats
Journal of Muscle Research and Cell Motility
Volume: 26
Page(s): 149-55
Year: 2005
Author(s): Sliwinski, A., Stanic, D., Finkelstein, D. I., Ilic, M., West, J. M., Dooley, P. C.
Author(s): Sliwinski, A., Stanic, D., Finkelstein, D. I., Ilic, M., West, J. M., Dooley, P. C.
Estrogen down-regulates glial activation in male mice following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxication
Brain Research
Volume: 1084
Page(s): 28-37
Year: 2006
Author(s): Tripanichkul, W., Sripanichkulchai, K., Finkelstein, D. I.
Author(s): Tripanichkul, W., Sripanichkulchai, K., Finkelstein, D. I.
Murine embryonic EGF-responsive ventral mesencephalic neurospheres display distinct regional specification and promote survival of dopaminergic neurons
Experimental Neurology
Volume: 199
Page(s): 209-21
Year: 2006
Author(s): Moses, D., Teper, Y., Gantois, I., Finkelstein, D. I., Horne, M. K., Drago, J.
Author(s): Moses, D., Teper, Y., Gantois, I., Finkelstein, D. I., Horne, M. K., Drago, J.
Null mutation of the alpha4 nicotinic receptor subunit increases the propensity of muscarinic-mediated neuronal bursting in mouse hippocampal slices
Neuropharmacology
Volume: 51
Page(s): 587-596
Year: 2006
Author(s): Reid, C. A., Coleman, H. A., Finkelstein, D. I., Horne, M. K., Drago, J.
Author(s): Reid, C. A., Coleman, H. A., Finkelstein, D. I., Horne, M. K., Drago, J.
P3-446: Significant reduction in 6-hydroxy-dopamine nigral lesion size by administration of clioquinol
Alzheimer's & Dementia
Volume: 2
Page(s): S507
Year: 2006
Estrogen protects against MPTP through glial attenuation
NEUROSCIENCE RESEARCH
Volume: 55
Page(s): S199--S199
Year: 2006
Dopaminergic innervation of the human striatum in Parkinson's disease
Movement Disorders
Volume: 20
Page(s): 810-8
Year: 2005
Author(s): Porritt, M., Stanic, D., Finkelstein, D., Batchelor, P., Lockhart, S., Hughes, A., Kalnins, R., Howells, D.
Author(s): Porritt, M., Stanic, D., Finkelstein, D., Batchelor, P., Lockhart, S., Hughes, A., Kalnins, R., Howells, D.
Haloperidol treatment reverses behavioural and anatomical changes in cocaine-dependent mice
Neurobiology of Disease
Volume: 19
Page(s): 301-11
Year: 2005
Author(s): Parish, C. L., Drago, J., Stanic, D., Borrelli, E., Finkelstein, D. I., Horne, M. K.
Author(s): Parish, C. L., Drago, J., Stanic, D., Borrelli, E., Finkelstein, D. I., Horne, M. K.
Mice Lacking the {alpha}4 Nicotinic Receptor Subunit Fail to Modulate Dopaminergic Neuronal Arbors and Possess Impaired Dopamine Transporter Function
Molecular Pharmacology
Year: 2005
Author(s): Parish, C. L., Nunan, J., Finkelstein, D. I., McNamara, F. N., Wong, J. Y., Waddington, J. L., Brown, R. M., Lawrence, A. J., Horne, M. K., Drago, J.
Author(s): Parish, C. L., Nunan, J., Finkelstein, D. I., McNamara, F. N., Wong, J. Y., Waddington, J. L., Brown, R. M., Lawrence, A. J., Horne, M. K., Drago, J.
Morphology and gelation of thermosensitive chitosan hydrogels
Biophysical Chemistry
Volume: 117
Page(s): 47-53
Year: 2005
Author(s): Crompton, K. E., Prankerd, R. J., Paganin, D. M., Scott, T. F., Horne, M. K., Finkelstein, D. I., Gross, K. A., Forsythe, J. S.
Author(s): Crompton, K. E., Prankerd, R. J., Paganin, D. M., Scott, T. F., Horne, M. K., Finkelstein, D. I., Gross, K. A., Forsythe, J. S.
Postural changes after lesions of the substantia nigra pars reticulata in hemiparkinsonian monkeys
Behavioural Brain Research
Volume: 160
Page(s): 267-76
Year: 2005
Author(s): Henderson, J. M., Stanic, D., Tomas, D., Patch, J., Horne, M. K., Bourke, D., Finkelstein, D. I.
Author(s): Henderson, J. M., Stanic, D., Tomas, D., Patch, J., Horne, M. K., Bourke, D., Finkelstein, D. I.
Chronic corticotropin-releasing factor type 1 receptor antagonism with antalarmin regulates the dopaminergic system of Fawn-Hooded rats
Journal of Neurochemistry
Volume: 94
Page(s): 1523–1534
Year: 2005
Author(s): Lawrence, A. J., Parish, C. L., Chen, F., Lodge, D. J., Krstew, E. V., Card, K., Finkelstein, D. I., Horne, M. K.
Author(s): Lawrence, A. J., Parish, C. L., Chen, F., Lodge, D. J., Krstew, E. V., Card, K., Finkelstein, D. I., Horne, M. K.
Glial responses associated with dopaminergic striatal reinnervation following lesions of the rat substantia nigra
Brain research
Volume: 1023
Page(s): 83--91
Year: 2004
Spontaneous Formation of Lewy Bodies in a Rodent
The Basal Ganglia VIII
Page(s): 321--329
Year: 2005
Differential expression of the GABA transporters GAT-1 and GAT-3 in brains of rats, cats, monkeys and humans| NOVA. The University of Newcastle's Digital Repository
Year: 2005
Glial glutamate transporter expression patterns in brains from multiple mammalian species| NOVA. The University of Newcastle's Digital Repository
Year: 2005
Merozoite surface proteins 4 and 5 of Plasmodium knowlesi have differing cellular localisation and association with lipid rafts
Molecular and biochemical parasitology
Volume: 138
Page(s): 153-8
Year: 2004
Author(s): Black, C. G., Wang, L., Topolska, A. E., Finkelstein, D. I., Horne, M. K., Thomas, A. W., Mohandas, N., Coppel, R. L.
Author(s): Black, C. G., Wang, L., Topolska, A. E., Finkelstein, D. I., Horne, M. K., Thomas, A. W., Mohandas, N., Coppel, R. L.
Neuronal nicotinic receptors: insights gained from gene knockout and knockin mutant mice
Cellular and Molecular Life Sciences
Volume: 60
Page(s): 1267-80
Year: 2003
Author(s): Drago, J., McColl, C. D., Horne, M. K., Finkelstein, D. I., Ross, S. A.
Author(s): Drago, J., McColl, C. D., Horne, M. K., Finkelstein, D. I., Ross, S. A.
Timecourse of striatal re-innervation following lesions of dopaminergic SNpc neurons of the rat
European Journal of Neuroscience
Volume: 18
Page(s): 1175-88
Year: 2003
Author(s): Stanic, D., Finkelstein, D. I., Bourke, D. W., Drago, J., Horne, M. K.
Author(s): Stanic, D., Finkelstein, D. I., Bourke, D. W., Drago, J., Horne, M. K.
A mouse model of spinal and bulbar muscular atrophy
Human Molecular Genetics
Volume: 11
Page(s): 2103-11
Year: 2002
Author(s): McManamny, P., Chy, H. S., Finkelstein, D. I., Craythorn, R. G., Crack, P. J., Kola, I., Cheema, S. S., Horne, M. K., Wreford, N. G., O'Bryan, M. K., De Kretser, D. M., Morrison, J. R.
Author(s): McManamny, P., Chy, H. S., Finkelstein, D. I., Craythorn, R. G., Crack, P. J., Kola, I., Cheema, S. S., Horne, M. K., Wreford, N. G., O'Bryan, M. K., De Kretser, D. M., Morrison, J. R.
Quantified assessment of terminal density and innervation
Current protocols in neuroscience
Volume: Chapter 1
Page(s): Unit 1 13
Year: 2004
Author(s): Finkelstein, D. I., Stanic, D., Parish, C. L., Drago, J., Horne, M. K.
Author(s): Finkelstein, D. I., Stanic, D., Parish, C. L., Drago, J., Horne, M. K.
Changes in function and ultrastructure of striatal dopaminergic terminals that regenerate following partial lesions of the SNpc
Journal of Neurochemistry
Volume: 86
Page(s): 329-43
Year: 2003
Author(s): Stanic, D., Parish, C. L., Zhu, W. M., Krstew, E. V., Lawrence, A. J., Drago, J., Finkelstein, D. I., Horne, M. K.
Author(s): Stanic, D., Parish, C. L., Zhu, W. M., Krstew, E. V., Lawrence, A. J., Drago, J., Finkelstein, D. I., Horne, M. K.
Electroencephalographic characterisation of pentylenetetrazole-induced seizures in mice lacking the [alpha] 4 subunit of the neuronal nicotinic receptor
Neuropharmacology
Volume: 44
Page(s): 234--243
Year: 2003
D2 Dopamine receptor blockade results in sprouting of DA axons in the intact animal but prevents sprouting following nigral lesions
European Journal of Neuroscience
Volume: 17
Page(s): 1033--1045
Year: 2003
Glutamate transporter expression patterns vary in mammals with differing levels of cortical complexity
Society for Neuroscience Annual Meeting 2004
Year: 2004
Dopamine dynamic changes and behavioural assessment in advanced Parkinson's disease and levodopa induced dyskinesia models
JOURNAL OF NEUROCHEMISTRY
Volume: 87
Page(s): 103--103
Year: 2003
Effects of long-term treatment with dopamine receptor agonists and antagonists on terminal arbor size
European Journal of Neuroscience
Volume: 16
Page(s): 787-94
Year: 2002
Author(s): Parish, C. L., Stanic, D., Drago, J., Borrelli, E., Finkelstein, D. I., Horne, M. K.
Author(s): Parish, C. L., Stanic, D., Drago, J., Borrelli, E., Finkelstein, D. I., Horne, M. K.
The role of interleukin-1, interleukin-6, and glia in inducing growth of neuronal terminal arbors in mice
Journal of Neuroscience
Volume: 22
Page(s): 8034-41
Year: 2002
Author(s): Parish, C. L., Finkelstein, D. I., Tripanichkul, W., Satoskar, A. R., Drago, J., Horne, M. K.
Author(s): Parish, C. L., Finkelstein, D. I., Tripanichkul, W., Satoskar, A. R., Drago, J., Horne, M. K.
The role of dopamine receptors in regulating the size of axonal arbors
Journal of Neuroscience
Volume: 21
Page(s): 5147-57.
Year: 2001
Author(s): Parish, C. L., Finkelstein, D. I., Drago, J., Borrelli, E., Horne, M. K.
Author(s): Parish, C. L., Finkelstein, D. I., Drago, J., Borrelli, E., Horne, M. K.
Comparison of the basal ganglia in rats, marmosets, macaques, baboons, and humans: volume and neuronal number for the output, internal relay, and striatal modulating nuclei
The Journal of comparative neurology
Volume: 445
Page(s): 238--255
Year: 2002
Projections from the substantia nigra pars reticulata to the motor thalamus of the rat: single axon reconstructions and immunohistochemical study
The Journal of comparative neurology
Volume: 440
Page(s): 20--30
Year: 2001
Proconvulsant-induced seizures in [alpha] 4 nicotinic acetylcholine receptor subunit knockout mice
Neuropharmacology
Volume: 43
Page(s): 55--64
Year: 2002
The role of dopamine receptors in regulating the size of axonal arbours
ADVANCES IN BEHAVIORAL BIOLOGY
Volume: 52
Page(s): 313--322
Year: 2002
Kainate receptors, cellular signaling and excitotoxic neuronal death: New pharmacological evidence for the functional involvement of low-affinity and metabotropic kainate receptors
Excitatory Amino Acids: Ten Years Later
Volume: 45
Page(s): 161--172
Year: 2001
Basal ganglia and cerebellar thalamic afferents
21st Annual Meeting of the Australian Neuroscience Society
Volume: 12
Page(s): 212--212
Year: 2001
Behavioural effects of neurosurgery to the substantia nigra pars reticulata in parkinsonian monkeys
MOVEMENT DISORDERS
Volume: 17
Page(s): S185--S185
Year: 2002
Axonal sprouting following lesions of the rat substantia nigra
Neuroscience
Volume: 97
Page(s): 99-112
Year: 2000
Author(s): Finkelstein, D. I., Stanic, D., Parish, C. L., Tomas, D., Dickson, K., Horne, M. K.
Author(s): Finkelstein, D. I., Stanic, D., Parish, C. L., Tomas, D., Dickson, K., Horne, M. K.
Nitrergic stimulation of the locus coeruleus modulates blood pressure and heart rate in the anaesthetized rat
Neuroscience
Volume: 91
Page(s): 621-9
Year: 1999
Author(s): Yao, S. T., Finkelstein, D. I., Lawrence, A. J.
Author(s): Yao, S. T., Finkelstein, D. I., Lawrence, A. J.
Neuronal activity in the monkey ventrolateral thalamus following perturbations of voluntary wrist movements
Experimental Brain Research
Volume: 118
Page(s): 393-407
Year: 1998
Author(s): Butler, E. G., Harvey, M. C., Finkelstein, D. I., Horne, M. K.
Author(s): Butler, E. G., Harvey, M. C., Finkelstein, D. I., Horne, M. K.
Regional distribution of low affinity kainate receptors in brain of Macaca fascicularis determined by autoradiography using [3H](2S,4R)-4- methylglutamate
Neuroscience Letters
Volume: 255
Page(s): 71-4.
Year: 1998
Author(s): Carroll, F. Y., Finkelstein, D. I., Horne, M. K., Lawrence, A. J., Crawford, D., Paxinos, G., Beart, P. M.
Author(s): Carroll, F. Y., Finkelstein, D. I., Horne, M. K., Lawrence, A. J., Crawford, D., Paxinos, G., Beart, P. M.
Comparative study on the distribution patterns of P2X(1)-P2X(6) receptor immunoreactivity in the brainstem of the rat and the common marmoset (Callithrix jacchus): association with catecholamine cell groups
Journal of Comparative Neurology
Volume: 427
Page(s): 485-507.
Year: 2000
Author(s): Yao, S. T., Barden, J. A., Finkelstein, D. I., Bennett, M. R., Lawrence, A. J.
Author(s): Yao, S. T., Barden, J. A., Finkelstein, D. I., Bennett, M. R., Lawrence, A. J.
Study of projections from the entopeduncular nucleus to the thalamus of the rat
Journal of Comparative Neurology
Volume: 426
Page(s): 366--377
Year: 2000
Sprouting of dopaminergic axons after striatal injury: confirmation by markers not dependent on dopamine metabolism
Experimental neurology
Volume: 159
Page(s): 565--573
Year: 1999
Early direct and transneuronal effects in mice with targeted expression of a toxin gene to D1 dopamine receptor neurons
Neuroscience
Volume: 95
Page(s): 1025--1033
Year: 1999
Immunohistochemistry with antibodies to the cholecystokinin-A receptor reveals a widespread distribution in rat and monkey central nervous system
NATO ASI SERIES A LIFE SCIENCES
Volume: 307
Page(s): 175--180
Year: 1999
Peptidergic G Protein-Coupled Receptors 175 P. Geppetti et al.(Eds.) IOS Press, 1999
Peptidergic G protein-coupled receptors: from basic research to clinical applications
Volume: 307
Page(s): 175
Year: 1999
A comparison of methods used to detect changes in neuronal discharge patterns
Journal of Neuroscience Methods
Volume: 76
Page(s): 203-210
Year: 1997
Author(s): Churchward, P. R., Butler, E. G., Finkelstein, D. I., Aumann, T. D., Sudbury, A., Horne, M. K.
Author(s): Churchward, P. R., Butler, E. G., Finkelstein, D. I., Aumann, T. D., Sudbury, A., Horne, M. K.
Leukemia inhibitory factor enhances the regeneration of transected rat sciatic nerve and the function of reinnervated muscle
Journal of Neuroscience Research
Volume: 47
Page(s): 208-15.
Year: 1997
Author(s): Tham, S., Dowsing, B., Finkelstein, D., Donato, R., Cheema, S. S., Bartlett, P. F., Morrison, W. A.
Author(s): Tham, S., Dowsing, B., Finkelstein, D., Donato, R., Cheema, S. S., Bartlett, P. F., Morrison, W. A.
Leukemia inhibitory factor is a myotrophic and neurotrophic agent that enhances the reinnervation of muscle in the rat
Journal of Neuroscience Research
Volume: 46
Page(s): 122-8
Year: 1996
Author(s): Finkelstein, D. I., Bartlett, P. F., Horne, M. K., Cheema, S. S.
Author(s): Finkelstein, D. I., Bartlett, P. F., Horne, M. K., Cheema, S. S.
An electron microscopic tracer study of the projections from entopeduncular nucleus to the ventrolateral nucleus of the rat
Neuroscience Letters
Volume: 211
Page(s): 33-6
Year: 1996
Author(s): Finkelstein, D. I., Reeves, A. K., Horne, M. K.
Author(s): Finkelstein, D. I., Reeves, A. K., Horne, M. K.
On the distribution of cholecystokinin B receptors in monkey brain
Brain Research
Volume: 738
Page(s): 313-8
Year: 1996
Author(s): Mercer, L. D., Beart, P. M., Horne, M. K., Finkelstein, D. I., Carrive, P., Paxinos, G.
Author(s): Mercer, L. D., Beart, P. M., Horne, M. K., Finkelstein, D. I., Carrive, P., Paxinos, G.
Targeted expression of a toxin gene to D1 dopamine receptor neurons by cre-mediated site-specific recombination
The Journal of neuroscience
Volume: 18
Page(s): 9845--9857
Year: 1998
FGF plays a subtle role in oligodendrocyte maintenance in vivo
Journal of neuroscience research
Volume: 49
Page(s): 404--415
Year: 1997
The effects of reversible inactivation of the subthalamo-pallidal pathway on the behaviour of naive and hemiparkinsonian monkeys
Journal of Clinical Neuroscience
Volume: 4
Page(s): 218--227
Year: 1997
The relationship between monkey ventrolateral thalamic nucleus activity and kinematic parameters of wrist movement
Brain research
Volume: 736
Page(s): 146--159
Year: 1996
Leukemia Inhibitory Factor (LIF) Enhances Peripheral Nerve Regeneration
SURGICAL FORUM-CHICAGO-
Page(s): 732--734
Year: 1995
The Role of leukaemia inhibitory factor (LIF) in rat peripheral nerve regeneration
Annals of the Academy of Medicine, Singapore
Volume: 24
Page(s): 94-100.
Year: 1995
Author(s): Donato, R., Cheema, S., Finkelstein, D., Bartlett, P., Morrison, W.
Author(s): Donato, R., Cheema, S., Finkelstein, D., Bartlett, P., Morrison, W.
Neural activity in the monkey anterior ventrolateral thalamus during trained, ballistic movements
Journal of Neurophysiology
Volume: 70
Page(s): 2276-88
Year: 1993
Author(s): Forlano, L. M., Horne, M. K., Butler, E. G., Finkelstein, D.
Author(s): Forlano, L. M., Horne, M. K., Butler, E. G., Finkelstein, D.
Recovery of muscle after different periods of denervation and treatments
Muscle and Nerve
Volume: 16
Page(s): 769-77
Year: 1993
Author(s): Finkelstein, D. I., Dooley, P. C., Luff, A. R.
Author(s): Finkelstein, D. I., Dooley, P. C., Luff, A. R.
Projections from the lateral and interposed cerebellar nuclei to the thalamus of the rat: a light and electron microscopic study using single and double anterograde labelling
The Journal of comparative neurology
Volume: 349
Page(s): 165--181
Year: 1994
Australian Stringhalt-epidemiological, clinical and neurological investigations
Equine veterinary journal
Volume: 21
Page(s): 266--273
Year: 1989
Developmental changes in hindlimb muscles and diaphragm of sheep
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Volume: 263
Page(s): R900--R908
Year: 1992
Effects of thyroidectomy on development of skeletal muscle in fetal sheep
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Volume: 261
Page(s): R1300--R1306
Year: 1991
Functional and structural changes of rat plantaris motoneurons following compensatory hypertrophy of the muscle
The Anatomical Record
Volume: 229
Page(s): 129--137
Year: 1991
The effect of a six day sucrose diet on isometric contractile characteristics and histochemistry of rat muscles
Journal of Animal Physiology and Animal Nutrition
Volume: 68
Page(s): 10--19
Year: 1992
Immunity to nerve growth factor and the effect on motor unit reinnervation in the rabbit
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Volume: 262
Page(s): R813--R818
Year: 1992
Contractile properties of cat motor units enlarged by motoneurone sprouting
Experimental brain research
Volume: 60
Page(s): 590--593
Year: 1985
Morphological and isometric properties of reinnervated motor units in hindlimb muscles of the cat
Year: 1984
Identifying novel roles in cell communication for disease-related proteins
Proceedings of the Australian Physiological Society http://www. aups. org. au/Proceedings
Volume: 40
Page(s): 38P
Plasticity of the Motor Unit
Year: 1989
Developmental changes in contractile function of the diaphragm in the pre-term lamb
Proceedings of the Australian Physiological Society http://www. aups. org. au/Proceedings
Volume: 39
Page(s): 78P
Effect of Electric Fields on Nerve Regeneration and Functional Recovery in the Cat Hindlimb
Molecular Pathology of Nerve and Muscle
Page(s): 119--134
Year: 1983
Properties of Cross and Self Reinnervating Motor Axons in the Cat
Molecular Pathology of Nerve and Muscle
Page(s): 135--149
Year: 1983
Roderick A. Westermanl David I. Finkelstein Deja Sriratana
Molecular Aspects of Neurological Disorders: Proceedings of an International Symposium, Held in Conjunction with the 12th International Congress of Biochemistry, 12-15 August 1982
Page(s): 95
Year: 1983
Molecular Aspects of Neurological Disorders: Proceedings of an International Symposium, Held in Conjunction with the 12th International Congress of Biochemistry, 12-15 August 1982
Year: 1983

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