PhD Student - Presynaptic Physiology
Ms Holly Melland
B.Sc (Hons)

I am interested in the proteins and processes that coordinate and sustain neurotransmitter release and how their dysfunction leads to neurological disorders.

My project particularly focuses on the presynaptic function of the Parkinson's Disease-associated protein alpha-synuclein, as well as how mutations in synaptotagmin-1 (SYT1) cause a distinct neurodevelopmental disorder.

I apply a combination of molecular biology, biochemistry and live and fixed cell fluorescence imaging of primary neuronal cultures to assay presynaptic activity.

  • Location

    Florey Institute of Neuroscience and Mental Health
    30 Royal Parade

Awards and achievements

International Society for Neurochemistry Travel Award 2019
Florey Postgraduate Travel Award 2019
Miller Postgraduate Travel Award 2018
Australian Government Research Training Program Scholarship
University of Melbourne Faculty of Science Dean's Honours Award for 2016

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