
Stuart received a B.Sc (Hons) majoring in Pharmacology from Monash University in 1998. He subsequently worked as a research assistant at West Virginia University throughout 1999-2000, before returning to Australia to earn a PhD in neuroscience from Monash University in 2005. His postdoctoral training was carried out within the Dept. of Physiology & Pharmacology at Oregon Health & Science University in Portland, Oregon from 2005-2011 in the Andresen laboratory with a CJ Martin fellowship and he was promoted to Research Assistant Professor in 2010. Stuart was recruited to the Florey to establish a laboratory in 2012 and is currently a senior research officer and lab head within the institute.
His primary interests are in neuronal signalling and synaptic integration. His research has concentrated on the viscerosensory system, with a particular focus on neural signals sent from the internal organs to the brain via the vagus nerve. The McDougall laboratory (aka viscerosensory lab) ultimately aims to manipulate behaviours (satiety, seizures, memory) and physiological outcomes (blood pressure) via selective modulation of viscerosensory signals. To this end the lab is currently pursuing optoceutical strategies to treat diseases such as obesity.
Involved grants:
· NHMRC Project grant “The vagus nerve and gut - brain interactions: the underpinnings of successful weight loss surgery through recruitment of Brown Adipose Tissue” 2019-22; as CIC, CIA Prof Brian Oldfield.
- Florey ‘near miss’ scheme. Top ranked application based on NHMRC scores. 2017.
- Australian Research Council Discovery Project “Inhibition of sensory relay mechanisms.” 2017-19; as CIB, CIA A/Prof. Mathias Dutschmann.
- NHMRC Project grant “A potential analgesic target in a novel clinically-relevant neuropathic pain pathway.” 2016-18; as CIB, CIA Dr Jenny Gunnersen.
- University of Melbourne Research Grant Support Scheme 2015.
- NHMRC Project grant “Understanding the origins of neurogenic hypertension” 2015-17; as CIB, CIA Dr Song Yoa.
- NHMRC Project grant ‘Salt, opiates and addiction’ 2015-17; as CIC, CIA Prof. Andrew Lawrence.
- Harold Mitchell Foundation Postdoctoral Travel Fellowship 2013.
- University of Melbourne Early Career Researcher Grants Scheme 2014.
- C.J. Martin Fellowship; 2006-8, 2011-13.
Florey Collaborators:
Prof. Andrew Lawrence, Dr Song Yao, A/Prof. Mathias Dutschmann, A/Prof. Clare Parish, A/Prof. Lachlan Thompson, Prof. Ross Bathgate.
External Collaborators:
Prof. Andrew Allen
A. Prof. James Peters
Dr Jenny Gunnerson
Research Papers
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Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner.Nature Communications
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The intersection of stress and reward: BNST modulation of aversive and appetitive states.Progress in neuro-psychopharmacology & biological psychiatry
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Viscerosensory input drives angiotensin II type 1A receptor expressing neurons in the solitary tract nucleus.American journal of physiology. Regulatory, integrative and comparative physiology
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Functional and neurochemical characterization of angiotensin type 1A receptor-expressing neurons in the nucleus of the solitary tract of the mouse.American journal of physiology. Regulatory, integrative and comparative physiology
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Characterization of the relaxin family peptide receptor 3 system in the mouse bed nucleus of the stria terminalisJournal of Comparative Neurology
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Extensive inhibitory gating of viscerosensory signals by a sparse network of somatostatin neuronsThe Journal of Neuroscience
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Extensive Inhibitory Gating of Viscerosensory Signals by a Sparse Network of Somatostatin NeuronsThe Journal of Neuroscience
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Organotypic Cocultures of Human Pluripotent Stem Cell Derived-Neurons with Mammalian Inner Ear Hair Cells and Cochlear Nucleus SlicesStem Cells International
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PreBötzinger complex neurons drive respiratory modulation of blood pressure and heart rateeLife
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A Chemogenetic Tool that Enables Functional Neural Circuit AnalysisCell Reports
Showing 10 of 42. VIEW ALL
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